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对用于冈崎主动脉新瓣叶形成术的两种不同缝合技术的体外评估。

An ex vivo evaluation of two different suture techniques for the Ozaki aortic neocuspidization procedure.

作者信息

Saisho Hiroyuki, Scharfschwerdt Michael, Schaller Tim, Reil Jan Christian, Ensminger Stephan, Fujita Buntaro, Aboud Anas

机构信息

Department of Cardiac and Thoracic Vascular Surgery, University Hospital of Schleswig-Holstein, Lübeck, Germany.

University of Lübeck, Lübeck, Germany.

出版信息

Interact Cardiovasc Thorac Surg. 2021 Oct 4;33(4):518-524. doi: 10.1093/icvts/ivab138.

Abstract

OBJECTIVES

We investigated the Ozaki procedure using a single interrupted suture technique (SST) and compared this with the standard continuous suture technique (CST) with regard to hydrodynamic valve performance. In addition, both techniques were compared with the native aortic valve (NAV).

METHODS

Effective orifice area, mean pressure gradient and leakage volume were evaluated in the NAV as well as after an Ozaki procedure using SST or CST in fresh swine aortic roots using a mock circulation loop. The NAV, SST and CST were evaluated under 4 defined hydrodynamic conditions.

RESULTS

Both suture techniques resulted in a similar effective orifice area under all conditions [for stroke volume of 70 ml: SST: 1.50 (1.35-1.87) vs CST: 1.57 (1.41-1.72) cm2, P = 0.8] and there were no significant differences between both suture techniques and the NAV (P > 0.05). Regarding mean pressure gradient, the Ozaki procedure with SST and CST showed no significant differences [7.23 (5.53-8.91) vs 7.04 (6.65-7.60) mmHg, P = 0.72] and there was no significant difference between both suture techniques and the NAV (P > 0.1). In leakage volume, there was no significant difference between SST and CST [4.49 (3.91-4.99) vs CST: 4.23 (3.58-4.87) ml/stroke, P = 0.34].

CONCLUSIONS

The Ozaki procedure with SST performed similarly to that with CST with regard to hydrodynamic performance. Our results suggest that the Ozaki procedure can be performed with SST instead of CST, which may be useful in patients with limited surgical exposure, such as a small annulus.

摘要

目的

我们研究了使用单间断缝合技术(SST)的尾崎手术,并在流体动力学瓣膜性能方面将其与标准连续缝合技术(CST)进行比较。此外,还将这两种技术与天然主动脉瓣(NAV)进行了比较。

方法

在新鲜猪主动脉根部,使用模拟循环回路,评估天然主动脉瓣以及采用SST或CST进行尾崎手术后的有效瓣口面积、平均压力阶差和漏血量。在4种定义的流体动力学条件下对天然主动脉瓣、SST和CST进行评估。

结果

在所有条件下,两种缝合技术的有效瓣口面积相似[对于70 ml的每搏量:SST为1.50(1.35 - 1.87)vs CST为1.57(1.41 - 1.72)cm²,P = 0.8],两种缝合技术与天然主动脉瓣之间均无显著差异(P > 0.05)。关于平均压力阶差,采用SST和CST的尾崎手术无显著差异[7.23(5.53 - 8.91)vs 7.04(6.65 - 7.60)mmHg,P = 0.72],两种缝合技术与天然主动脉瓣之间也无显著差异(P > 0.1)。在漏血量方面,SST和CST之间无显著差异[4.49(3.91 - 4.99)vs CST:4.23(3.58 - 4.87)ml/每搏,P = 0.34]。

结论

在流体动力学性能方面,采用SST的尾崎手术与采用CST的手术表现相似。我们的结果表明,尾崎手术可以采用SST而非CST进行,这对于手术暴露受限的患者(如瓣环较小的患者)可能有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a9e/8923410/fcf097f42cc7/ivab138f5.jpg

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