Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
J AAPOS. 2021 Aug;25(4):236-239. doi: 10.1016/j.jaapos.2021.03.003. Epub 2021 Jun 2.
Reversal of optic nerve head (ONH) cupping has been considered an important clinical observation that signals surgical success and control of intraocular pressure (IOP) in childhood glaucoma. Many theories based on elasticity of pediatric eyes have been proposed, including anterior movement of the elastic lamina cribrosa or shrinkage of the scleral canal. The relationship between these factors and axonal loss is unclear when reversal of cupping has been observed. Retinal nerve fiber layer (RNFL) optical coherence tomography (OCT) can help to clarify this. We present a case series of 4 pediatric patients with secondary glaucoma that demonstrated ONH cupping reversal with pre- and postoperative clinical images and RNFL OCT.
视盘（ONH）杯状逆转已被认为是一个重要的临床观察指标，表明儿童青光眼的手术成功和眼压（IOP）得到控制。许多基于小儿眼球弹性的理论已经被提出，包括弹性筛板前移位或巩膜管收缩。当观察到杯状逆转时，这些因素与轴突丢失之间的关系尚不清楚。视网膜神经纤维层（RNFL）光学相干断层扫描（OCT）可以帮助阐明这一点。我们报告了 4 例继发性青光眼患儿的病例系列，这些患儿在术前和术后的临床图像以及 RNFL OCT 中显示出 ONH 杯状逆转。
