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印度尼西亚一家三级医院两例气管支气管乳头状瘤病的治疗:病例报告

Management of two cases of tracheobronchial management of two cases of tracheobronchial papillomatosis at tertiary hospital in Indonesia: A case report.

作者信息

Perdana Rizka Fathoni

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Indonesia.

出版信息

Int J Surg Case Rep. 2021 Jun;83:106054. doi: 10.1016/j.ijscr.2021.106054. Epub 2021 May 29.

DOI:10.1016/j.ijscr.2021.106054
PMID:34090191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8188390/
Abstract

INTRODUCTION AND IMPORTANCE

Tracheobronchial papillomatosis is an aggressive form of RRP with the spread of papillomas to the subglottis, trachea, bronchus and pulmonary parehchyma. Surgical operation for removing the papilloma is extremely difficult and need a lot of periodical bronchoscopy.

CASE PRESENTATION

The first patient was a 25-year-old male who had an RRP history since the age of 6 months. Patients undergo papilloma cleaning surgery every 2 to 4 months. So far, the patient has undergone 88 operations. The frequency of surgery did not decrease even though the patient had reached adulthood. Moreover, the second patient was a 9-year-old woman suffering from RRP since the age of 6 months. The history of surgery has been carried out four times. The patient did not regularly go to the hospital. Consequently, the papilloma blocked the airway and the patient underwent tracheotomy at 3 years-old. A recent endoscopic examination showed papillomas growing in the trachea so that the tracheal stoma was maintained at this time to keep the upper airway patent and access for surgery.

CLINICAL DISCUSSION

Endoscopic removal surgery is required for larynx and tracheobronchial papillomas. Debulking through bronchoscopy regularly in order to maintain the airway patency. Tracheal stoma is needed for surgical access. Hence, accurate monitoring of disease progression and potential changes in malignancy is needed.

CONCLUSSION

Tracheobronchial papillomatosis is very rare disease that needs periodically surgery for clean the tumor and monitoring the possibility for malignancy.

摘要

引言与重要性

气管支气管乳头状瘤病是复发性呼吸道乳头状瘤病(RRP)的一种侵袭性形式,乳头状瘤会扩散至声门下、气管、支气管和肺实质。切除乳头状瘤的外科手术极具难度,且需要多次定期进行支气管镜检查。

病例介绍

首例患者为一名25岁男性,自6个月大起就患有RRP。患者每2至4个月接受一次乳头状瘤清除手术。截至目前,该患者已接受了88次手术。即便患者已成年,手术频率仍未降低。此外,第二例患者是一名9岁女性,自6个月大起就患有RRP。她已接受过4次手术。该患者未定期前往医院就诊。结果,乳头状瘤阻塞了气道,患者在3岁时接受了气管切开术。近期的内镜检查显示气管内有乳头状瘤生长,因此此时维持气管造口以保持上呼吸道通畅并便于手术操作。

临床讨论

喉及气管支气管乳头状瘤需要进行内镜切除手术。定期通过支气管镜进行减瘤操作以维持气道通畅。手术操作需要气管造口。因此,需要准确监测疾病进展以及恶性肿瘤的潜在变化。

结论

气管支气管乳头状瘤病是一种非常罕见的疾病,需要定期进行手术以清除肿瘤并监测恶变可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/68aa2b9a174f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/5d254fc2d896/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/d79c3342ae1a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/710960277d5d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/68aa2b9a174f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/5d254fc2d896/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/d79c3342ae1a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/710960277d5d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2607/8188390/68aa2b9a174f/gr4.jpg

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