Biggs Quinn M, Ursano Robert J, Wang Jing, Wynn Gary H, Amin Rohul, Fullerton Carol S
Center for the Study of Traumatic Stress (CSTS), Department of Psychiatry, Uniformed Services University of the Health Sciences (USUHS), 4301 Jones Bridge Road, Bethesda, MD, 20814, USA.
Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF), Bethesda, MD, USA.
BMC Psychiatry. 2021 Jun 5;21(1):292. doi: 10.1186/s12888-021-03282-3.
Sleep disturbances are common in individuals with post traumatic stress disorder (PTSD). However, little is known about how daily variation in sleep characteristics is related to PTSD. This study examined the night-to-night and weekday versus weekend variation in sleep duration, sleep quality, trouble falling asleep, and difficulty staying asleep in individuals with and without PTSD.
Participants (N = 157; 80 with PTSD, 77 without PTSD) completed daily self-reports of their nighttime sleep characteristics for 15 consecutive days. Linear mixed models were used to examine the associations between the 7 days of the week and weekday versus weekend variation in sleep characteristics and PTSD.
Individuals with PTSD reported shorter sleep duration, lower sleep quality, more trouble falling asleep, and more difficulty staying asleep than individuals without PTSD. The pattern of change across the week and between weekdays and weekends was different between those with and without PTSD for sleep quality and trouble falling asleep. Among those with PTSD, sleep duration, sleep quality, and trouble falling asleep differed across the 7 days of the week and showed differences between weekdays and weekends. For those without PTSD, only sleep duration differed across the 7 days of the week and showed differences between weekdays and weekends. Neither group showed 7 days of the week nor weekday versus weekend differences in difficulty staying asleep.
On average those with PTSD had shorter sleep duration, poorer sleep quality, and greater trouble falling and staying asleep. In particular, the day of week variation in sleep quality and trouble falling asleep specifically distinguishes those with PTSD from those without PTSD. Our findings suggest that clinical care might be improved by assessments of sleep patterns and disturbances across at least a week, including weekdays and weekends. Future studies should explore the mechanisms related to the patterns of sleep disturbance among those with PTSD.
睡眠障碍在创伤后应激障碍(PTSD)患者中很常见。然而,关于睡眠特征的每日变化与PTSD之间的关系却知之甚少。本研究调查了有无PTSD个体在睡眠时间、睡眠质量、入睡困难和睡眠维持困难方面的夜间变化以及工作日与周末的差异。
参与者(N = 157;80例PTSD患者,77例无PTSD者)连续15天每天自行报告夜间睡眠特征。使用线性混合模型来研究一周中的7天与工作日和周末睡眠特征及PTSD变化之间的关联。
与无PTSD的个体相比,PTSD患者报告的睡眠时间更短、睡眠质量更低、入睡困难更多以及睡眠维持困难更多。在睡眠质量和入睡困难方面,有PTSD和无PTSD个体在一周内以及工作日与周末之间的变化模式不同。在PTSD患者中,睡眠时间、睡眠质量和入睡困难在一周的7天内有所不同,并且在工作日和周末之间也存在差异。对于无PTSD的个体,只有睡眠时间在一周的7天内有所不同,并且在工作日和周末之间也存在差异。两组在睡眠维持困难方面均未表现出一周内或工作日与周末的差异。
平均而言,PTSD患者的睡眠时间更短、睡眠质量更差,入睡和维持睡眠的困难更大。特别是,睡眠质量和入睡困难的周内变化具体区分了有PTSD和无PTSD的个体。我们的研究结果表明,通过评估至少一周内包括工作日和周末的睡眠模式和障碍,可能会改善临床护理。未来的研究应探索与PTSD患者睡眠障碍模式相关的机制。