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肥胖患者手术期间的术中监测:叙述性综述。

Intraoperative Monitoring of the Obese Patient Undergoing Surgery: A Narrative Review.

机构信息

Department of Anaesthesia, St Vincent's University Hospital, Dublin 4, Dublin, Ireland.

University of Campania "Luigi Vanvitelli", Naples, Italy.

出版信息

Adv Ther. 2021 Jul;38(7):3622-3651. doi: 10.1007/s12325-021-01774-y. Epub 2021 Jun 5.

Abstract

With the increasing prevalence of obesity in the population, anaesthetists must confidently manage both the pathophysiological and technical challenges presented in bariatric and non-bariatric surgery. The intraoperative period represents an important opportunity to optimise and mitigate risk. However, there is little formal guidance on what intraoperative monitoring techniques should be used in this population. This narrative review collates the existing evidence for intraoperative monitoring devices in the obese patients. Although a number of non-invasive blood pressure monitors have been tested, an invasive arterial line remains the most reliable monitor if accurate, continuous monitoring is required. Goal-directed fluid therapy is recommended by clinical practice guidelines, but the methods tested to assess this had guarded applicability to the obese population. Transcutaneous carbon dioxide (CO) monitoring may offer additional benefit to standard capnography in this population. Individually titrated positive end expiratory pressure (PEEP) and recruitment manoeuvres improved intraoperative mechanics but yielded no benefit in the immediate postoperative period. Depth of anaesthesia monitoring appears to be beneficial in the perioperative period regarding recovery times and complications. Objective confirmation of reversal of neuromuscular blockade continues to be a central tenet of anaesthesia practice, particularly relevant to this group who have been characterised as an "at risk" extubation group. Where deep neuromuscular blockade is used, continuous neuromuscular blockade is suggested. Both obesity and the intraoperative context represent somewhat unstable search terms, as the clinical implications of the obesity phenotype are not uniform, and the type and urgency of surgery have significant impact on the intraoperative setting. This renders the generation of summary conclusions around what intraoperative monitoring techniques are suitable in this population highly challenging.

摘要

随着人群中肥胖症的患病率不断增加,麻醉师必须有信心地管理肥胖症和非肥胖症手术中出现的病理生理和技术挑战。手术期间是优化和降低风险的重要机会。然而,对于该人群应使用哪些术中监测技术,几乎没有正式的指导。本叙述性综述汇集了肥胖患者术中监测设备的现有证据。尽管已经测试了许多非侵入性血压监测仪,但如果需要准确、连续的监测,则有创动脉线仍然是最可靠的监测仪。临床实践指南建议进行目标导向的液体治疗,但用于评估这一点的方法在肥胖人群中适用性有限。经皮二氧化碳(CO)监测在该人群中可能比标准呼气末二氧化碳监测提供额外的益处。个体化滴定呼气末正压(PEEP)和复张手法改善了术中力学,但在术后即刻无获益。麻醉深度监测似乎在围手术期恢复时间和并发症方面有益。神经肌肉阻滞逆转的客观确认仍然是麻醉实践的核心原则,特别是对于那些被认为是“有风险”拔管组的人群。在使用深度神经肌肉阻滞的情况下,建议持续神经肌肉阻滞。肥胖症和手术期间都是有些不稳定的搜索词,因为肥胖表型的临床意义并不统一,手术的类型和紧迫性对手术期间的环境有重大影响。这使得在该人群中适合哪些术中监测技术生成总结结论极具挑战性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e61/8280046/bcb2603934ac/12325_2021_1774_Fig1_HTML.jpg

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