Sroujieh A S
Department of Surgery, Faculty of Medicine, Jordan University, Amman.
Cancer. 1988 Sep 15;62(6):1247-50. doi: 10.1002/1097-0142(19880915)62:6<1247::aid-cncr2820620633>3.0.co;2-k.
A 55-year-old male patient who had melena and intussusception that proved to be due to malignant melanoma of the small intestine is described. History and close examination failed to show any evidence of a primary lesion. The diagnosis was made after a biopsy was performed on two lesions in the neck. This was followed by a palliative and incomplete resection of an involved ileal segment. The patient did not receive chemotherapy, radiotherapy, or immunotherapy. He is now alive 8 years after diagnosis without evidence of malignancy. This case represents spontaneous regression of malignant melanoma of the small intestine that is considered either a primary intestinal tumor or a metastatic tumor from an occult regressed primary. The latter assumption makes this case unique in that spontaneous regression occurred twice, once in the occult primary lesion and once in the intestinal metastases.
本文描述了一名55岁男性患者，该患者出现黑便和肠套叠，经证实是由小肠恶性黑色素瘤引起的。病史及详细检查均未发现任何原发性病变的证据。在对颈部的两个病变进行活检后做出了诊断。随后对受累的回肠段进行了姑息性不完全切除。该患者未接受化疗、放疗或免疫治疗。诊断后8年，他仍然存活，且无恶性肿瘤迹象。该病例代表了小肠恶性黑色素瘤的自发消退，这种肿瘤被认为要么是原发性肠道肿瘤，要么是来自隐匿性消退原发性肿瘤的转移瘤。后一种假设使得该病例具有独特性，即自发消退发生了两次，一次在隐匿性原发性病变中，一次在肠道转移灶中。
