Hussain Iram, Ahmad Shahzad, Aljammal Jules
Division of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
The Thyroid Clinic, Salt Lake City, Utah.
AACE Clin Case Rep. 2021 Jan 13;7(3):195-199. doi: 10.1016/j.aace.2021.01.002. eCollection 2021 May-Jun.
To present radiofrequency ablation (RFA) of parathyroid adenomas as a safe and effective management strategy for primary hyperparathyroidism in patients who are not eligible for surgery or those who do not want surgery.
The diagnosis of primary hyperparathyroidism was confirmed by laboratory investigations. A bone density scan showed osteoporosis, which was an indication for the surgical treatment of primary hyperparathyroidism. Ultrasonography of the neck was done to localize the parathyroid adenoma, after which RFA was performed to shrink the adenoma. Laboratory investigations were performed 10 days, 6 months, and 12 months after the procedure. A literature review was also conducted, and other reports of primary hyperparathyroidism cases treated with RFA were identified.
Biochemical cure of primary hyperparathyroidism was achieved by normalization of calcium levels, resolution of symptoms, elimination of complications, and decrease in the volume of the parathyroid adenoma.
RFA of parathyroid adenomas is a viable alternative to parathyroidectomy in patients who do not meet the criteria for surgery or do not wish to undergo surgery.
对于不符合手术条件或不愿接受手术的原发性甲状旁腺功能亢进患者，介绍甲状旁腺腺瘤的射频消融术（RFA）作为一种安全有效的治疗策略。
通过实验室检查确诊原发性甲状旁腺功能亢进。骨密度扫描显示骨质疏松，这是原发性甲状旁腺功能亢进手术治疗的指征。对颈部进行超声检查以定位甲状旁腺腺瘤，之后进行RFA以缩小腺瘤。术后10天、6个月和12个月进行实验室检查。还进行了文献综述，并确定了其他用RFA治疗原发性甲状旁腺功能亢进病例的报告。
通过钙水平正常化、症状缓解、并发症消除以及甲状旁腺腺瘤体积减小，实现了原发性甲状旁腺功能亢进的生化治愈。
对于不符合手术标准或不愿接受手术的患者，甲状旁腺腺瘤的RFA是甲状旁腺切除术的可行替代方法。
