Wang Zi-Lu, Wang Ying, Xu Jian-Lin, Zhao Meng, Dai Kai-Yang, Shan Cui-Cui, Xu Yun-He
Department of Chemistry and Hefei National Laboratory for Physical Sciences at Microscale, University of Science and Technology of China, Hefei 230026, P.R. China.
State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
Org Lett. 2021 Jun 18;23(12):4736-4742. doi: 10.1021/acs.orglett.1c01455. Epub 2021 Jun 7.
Unprecedented copper-catalyzed regiodivergent hydrosilylation reactions of substituted 1,3-dienes with hydrosilanes have been developed. The 1,2- and 1,4-hydrosilylations of 1-(hetero)aryl-substituted 1,3-dienes were highly selectively controlled via variation of the catalytic systems. Meanwhile, the 1,4-hydrosilylation reaction of 2-aryl-substituted 1,3-dienes with diphenylsilane was also successfully realized for the first time. These methods provide convenient and efficient approaches for the synthesis of structurally diverse allylsilanes.
已开发出前所未有的铜催化取代1,3 - 二烯与硅烷的区域发散性硅氢化反应。通过改变催化体系，可高度选择性地控制1 - （杂）芳基取代的1,3 - 二烯的1,2 - 和1,4 - 硅氢化反应。同时，首次成功实现了2 - 芳基取代的1,3 - 二烯与二苯基硅烷的1,4 - 硅氢化反应。这些方法为合成结构多样的烯丙基硅烷提供了方便有效的途径。
Zotero 插件