Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Weizmann Institute of Science, Rehovot, Israel.
Anaesthesist. 2021 Dec;70(Suppl 1):68-73. doi: 10.1007/s00101-021-00983-y. Epub 2021 Jun 7.
Aortic arch repair for aortic dissection is still associated with a high mortality rate. Providing adequate means of neuromonitoring to guide cerebral hemodynamics is advantageous, especially during selective anterior cerebral perfusion (SACP).
We aimed to investigate an easy multimodal neuromonitoring set-up consisting of processed electroencephalography (EEG), near infrared spectroscopy (NIRS), and transcranial doppler sonography (TCD).
We collected intraoperative data from six patients undergoing surgery for aortic dissection. In addition to standard hemodynamic monitoring, patients underwent continuous bilateral NIRS, processed EEG with bispectral index (BIS), and intermittent transcranial doppler sonography of the medial cerebral artery (MCA) with a standard B‑mode ultrasound device. Doppler measurements were taken bilaterally before cardiopulmonary bypass (CPB), during CPB, and during SACP at regular intervals.
Of the patients four survived without neurological deficits while two suffered fatal outcomes. Of the survivors two suffered from transient postoperative delirium. Multimodal monitoring led to a change in CPB flow or cannula repositioning in three patients. Left-sided mean flow velocities of the MCA decreased during SACP, as did BIS values.
Monitoring consisting of BIS, NIRS, and TCD may have an impact on hemodynamic management in aortic arch operations.
主动脉弓修复术治疗主动脉夹层仍然与高死亡率相关。提供足够的神经监测手段来指导脑血流动力学是有利的,特别是在选择性大脑前灌注(SACP)期间。
我们旨在研究一种由处理后的脑电图(EEG)、近红外光谱(NIRS)和经颅多普勒超声(TCD)组成的简便多模态神经监测设置。
我们从六名接受主动脉夹层手术的患者中收集了术中数据。除了标准的血流动力学监测外,患者还进行了双侧连续 NIRS、具有双谱指数(BIS)的处理 EEG 和间歇性经颅多普勒超声(MCA)的内侧大脑动脉(MCA),使用标准的 B 型超声设备。在体外循环(CPB)前、CPB 期间和 SACP 期间以固定间隔进行双侧多普勒测量。
六名患者中有四名存活且无神经功能缺陷,两名患者死亡。在幸存者中,有两名患者发生短暂的术后谵妄。多模态监测导致三名患者改变 CPB 流量或重新定位导管。在 SACP 期间,MCA 的左侧平均流速下降,BIS 值也下降。
由 BIS、NIRS 和 TCD 组成的监测可能对主动脉弓手术中的血流动力学管理产生影响。