• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Hypoxia is a key regulator in liver cancer progression.

作者信息

Ma Lichun, Craig Amanda J, Heinrich Sophia

机构信息

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, USA.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, USA.

出版信息

J Hepatol. 2021 Sep;75(3):736-737. doi: 10.1016/j.jhep.2021.05.032. Epub 2021 Jun 19.

DOI:10.1016/j.jhep.2021.05.032
PMID:34097995
Abstract
摘要

相似文献

1
Hypoxia is a key regulator in liver cancer progression.缺氧是肝癌进展的关键调节因子。
J Hepatol. 2021 Sep;75(3):736-737. doi: 10.1016/j.jhep.2021.05.032. Epub 2021 Jun 19.
2
Phage display library selection of a hypoxia-binding scFv antibody for liver cancer metabolic marker discovery.用于发现肝癌代谢标志物的缺氧结合单链抗体片段(scFv)抗体的噬菌体展示文库筛选。
Oncotarget. 2016 Jun 21;7(25):38105-38121. doi: 10.18632/oncotarget.9460.
3
Hypoxia inducible factors in hepatocellular carcinoma.肝细胞癌中的缺氧诱导因子
Oncotarget. 2017 Jul 11;8(28):46691-46703. doi: 10.18632/oncotarget.17358.
4
HIF-1α promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment.在缺氧肿瘤微环境中,缺氧诱导因子-1α(HIF-1α)通过上调赖氨酰氧化酶样蛋白2(LOXL2)促进肝细胞癌中的血管生成拟态形成。
J Exp Clin Cancer Res. 2017 Apr 27;36(1):60. doi: 10.1186/s13046-017-0533-1.
5
Histone deacetylase 5 promotes the migration and invasion of hepatocellular carcinoma via increasing the transcription of hypoxia-inducible factor-1α under hypoxia condition.组蛋白去乙酰化酶5在缺氧条件下通过增加缺氧诱导因子-1α的转录促进肝细胞癌的迁移和侵袭。
Tumour Biol. 2017 Jun;39(6):1010428317705034. doi: 10.1177/1010428317705034.
6
Time-dependent effect of hypoxia on tumor progression and liver progenitor cell markers in primary liver tumors.缺氧对原发性肝癌肿瘤进展及肝祖细胞标志物的时间依赖性影响。
PLoS One. 2015 Mar 20;10(3):e0119555. doi: 10.1371/journal.pone.0119555. eCollection 2015.
7
Role of the hypoxia-related gene, JMJD1A, in hepatocellular carcinoma: clinical impact on recurrence after hepatic resection.缺氧相关基因 JMJD1A 在肝细胞癌中的作用:肝切除术后复发的临床影响。
Ann Surg Oncol. 2012 Jul;19 Suppl 3:S355-64. doi: 10.1245/s10434-011-1797-x. Epub 2011 May 24.
8
The role of hypoxia inducible factor-1 in hepatocellular carcinoma.缺氧诱导因子-1在肝细胞癌中的作用
Biomed Res Int. 2014;2014:409272. doi: 10.1155/2014/409272. Epub 2014 Jul 2.
9
The hypoxia conditioned mesenchymal stem cells promote hepatocellular carcinoma progression through YAP mediated lipogenesis reprogramming.缺氧条件下的间充质干细胞通过 YAP 介导的脂生成重编程促进肝癌进展。
J Exp Clin Cancer Res. 2019 May 29;38(1):228. doi: 10.1186/s13046-019-1219-7.
10
Knockdown of FRAT1 inhibits hypoxia-induced epithelial-to-mesenchymal transition via suppression of the Wnt/β-catenin pathway in hepatocellular carcinoma cells.敲低FRAT1可通过抑制肝癌细胞中的Wnt/β-连环蛋白信号通路来抑制缺氧诱导的上皮-间质转化。
Oncol Rep. 2016 Nov;36(5):2999-3004. doi: 10.3892/or.2016.5130. Epub 2016 Sep 23.

引用本文的文献

1
Reactive oxygen species in cancer: Mechanistic insights and therapeutic innovations.癌症中的活性氧:机制洞察与治疗创新
Cell Stress Chaperones. 2025 Aug 5;30(5):100108. doi: 10.1016/j.cstres.2025.100108.
2
The diagnositic value of dynamic contrast-enhanced ultrasound for evaluation of tissue oxygen status in rat hepatoma model.动态对比增强超声评估大鼠肝癌模型组织氧状态的诊断价值。
BMC Gastroenterol. 2024 Nov 23;24(1):424. doi: 10.1186/s12876-024-03523-1.
3
is regulated by miR-642a-5p and promotes pancreatic cancer progression through the Wnt/β-catenin pathway.
受miR-642a-5p调控,并通过Wnt/β-连环蛋白途径促进胰腺癌进展。
iScience. 2024 Aug 22;27(9):110782. doi: 10.1016/j.isci.2024.110782. eCollection 2024 Sep 20.
4
Tumor battlefield within inflamed, excluded or desert immune phenotypes: the mechanisms and strategies.炎症性、排除性或无反应性免疫表型中的肿瘤微环境:机制与策略
Exp Hematol Oncol. 2024 Aug 6;13(1):80. doi: 10.1186/s40164-024-00543-1.
5
Hypoxia-activated selectivity-improved anti-PKM2 antibody combined with prodrug TH-302 for potentiated targeting therapy in hepatocellular carcinoma.缺氧激活的选择性改善的抗 PKM2 抗体与前药 TH-302 联合用于增强肝细胞癌的靶向治疗。
Int J Biol Sci. 2024 Feb 11;20(5):1634-1651. doi: 10.7150/ijbs.92211. eCollection 2024.
6
In-situ-sprayed therapeutic hydrogel for oxygen-actuated Janus regulation of postsurgical tumor recurrence/metastasis and wound healing.用于氧驱动的原位喷雾治疗水凝胶对术后肿瘤复发/转移和伤口愈合的双面调节
Nat Commun. 2024 Jan 27;15(1):814. doi: 10.1038/s41467-024-45072-x.
7
Neutrophil extracellular traps induced by the hypoxic microenvironment in gastric cancer augment tumour growth.低氧微环境诱导的中性粒细胞胞外诱捕网促进胃癌肿瘤生长。
Cell Commun Signal. 2023 May 1;21(1):86. doi: 10.1186/s12964-023-01112-5.
8
Hypoxia signaling in cancer: Implications for therapeutic interventions.癌症中的缺氧信号传导:对治疗干预的意义。
MedComm (2020). 2023 Jan 23;4(1):e203. doi: 10.1002/mco2.203. eCollection 2023 Feb.
9
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression.microRNA-223 通过阻断缺氧驱动的血管生成和免疫抑制来抑制肝癌发生。
Gut. 2023 Oct;72(10):1942-1958. doi: 10.1136/gutjnl-2022-327924. Epub 2023 Jan 2.
10
Blood Supply and Oxygenation Status of the Liver: From Physiology to Malignancy.肝脏的血液供应和氧合状态:从生理学到恶性肿瘤。
Adv Exp Med Biol. 2022;1395:263-267. doi: 10.1007/978-3-031-14190-4_43.