Lisianyĭ N I, Markova O V, Zhmareva E N
Eksp Onkol. 1988;10(3):57-9.
Activity of natural killer cells (NK-cells) was determined in a 4-hour 51Cr-release test using K-562 as target cells in patients with brain tumours and donors. This activity was significantly (P less than 0.05) reduced in preoperative patients with metastatic brain tumours (mean--5.7%), gliomas of III-IV malignancy grades (mean--16.4%) as compared with the control (mean--32.5%). The activity of NK-cells remained low after surgical treatment irrespective of the length of remission.
在一项4小时的51Cr释放试验中，以K-562作为靶细胞，测定了脑肿瘤患者和供体中自然杀伤细胞（NK细胞）的活性。与对照组（平均32.5%）相比，术前转移性脑肿瘤患者（平均5.7%）、III-IV级恶性胶质瘤患者（平均16.4%）的NK细胞活性显著降低（P<0.05）。无论缓解期长短，手术治疗后NK细胞活性仍维持在较低水平。
