Department of Urology, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, China.
J Endourol. 2022 Jan;36(1):143-150. doi: 10.1089/end.2021.0048.
To evaluate the efficacy and safety of performing extracorporeal physical vibrational lithecbole (EPVL) through greater sciatic foramen (GSF) for distal ureteral calculi (DUC) treatment. All patients with a diagnosis of DUC (6-10 mm in diameter) were enrolled in this study from October 2018 to May 2020. Patients were randomly divided into three groups receiving EPVL through GSF (Group A, = 58), or abdominal (Group B, = 60), or combined with oral use of tamsulosin at 0.4 mg daily (Group C, = 63). There was no significant difference observed in terms of demographic characteristics or size of stones among the three groups ( > 0.05). Compared with the Groups B and C, patients of the Group A displayed a significantly higher score of comfort, with a significantly decreased number of renal colic attacks or analgesics required ( < 0.01). The stone-free rate also significantly increased after 1 and 2 weeks of treatment ( < 0.01), despite such a significant difference among these groups vanishing after 4 weeks of treatment. EPVL in the prone position uses the GSF as the path and is a safe and effective approach to treat the distal ureteral calculi.
评估经大坐骨切迹（GSF）行体外物理振动碎石术（EPVL）治疗远端输尿管结石（DUC）的疗效和安全性。
所有被诊断为 DUC（直径 6-10mm）的患者均于 2018 年 10 月至 2020 年 5 月期间被纳入本研究。患者被随机分为三组，分别接受经 GSF（A 组， = 58）、腹部（B 组， = 60）或联合每日口服坦索罗辛 0.4mg（C 组， = 63）行 EPVL 治疗。三组患者的人口统计学特征或结石大小均无显著差异（ > 0.05）。与 B 组和 C 组相比，A 组患者舒适度评分显著更高，肾绞痛发作次数或所需止痛药的数量显著减少（ < 0.01）。治疗 1 周和 2 周后，结石清除率也显著增加（ < 0.01），尽管治疗 4 周后，这些组之间的差异消失。
俯卧位 EPVL 采用 GSF 作为路径，是一种安全有效的治疗远端输尿管结石的方法。
