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肝片形吸虫病误诊为肝癌破裂出血 1 例

A case of hepatic paragonimiasis was misdiagnosed as hepatocellular carcinoma with rupture and haemorrhage.

机构信息

Department of Hepatobiliary Surgery, Second Clinical College, Kunming Medical University, The Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan Province, China.

Department of Hepatobiliary Surgery, Kunming Medical University, The Second Affiliated Hospital of Kunming Medical College, Kunming, Yunnan Province, China.

出版信息

J Int Med Res. 2021 Jun;49(6):3000605211012668. doi: 10.1177/03000605211012668.

DOI:10.1177/03000605211012668
PMID:34098756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8191090/
Abstract

Paragonimiasis is a disease caused by parasitic infections that mainly involve the lungs. However, it can also produce ectopic infections, such as when the parasites invade the liver, brain and subcutaneous tissue, which then cause different symptoms. This current case report describes a 55-year-old male patient with hepatic paragonimiasis that was misdiagnosed as liver cancer with rupture and haemorrhage. The initial computed tomography findings suggested ruptured liver cancer. The patient underwent laparoscopic right hemihepatectomy. Postoperative pathological analysis resulted in a diagnosis of hepatic paragonimiasis. The patient recovered well postoperatively and was treated with 25 mg/kg praziquantel orally three times a day for 3 days after discharge with good efficacy. In this present case, the rupture and haemorrhage of the liver mass made it difficult for the treating physicians to consider hepatic paragonimiasis, which lead to the initial misdiagnosis of this patient. Although paragonimiasis is very rare, medical staff should be vigilant and have a comprehensive understanding of the different diseases that can cause liver masses so that misdiagnosis can be avoided.

摘要

并殖吸虫病是一种由寄生虫感染引起的疾病,主要涉及肺部。然而,它也会产生异位感染,例如当寄生虫侵入肝脏、大脑和皮下组织时,就会导致不同的症状。本病例报告描述了一名 55 岁男性患者,患有肝并殖吸虫病,被误诊为肝癌破裂出血。最初的计算机断层扫描结果提示肝癌破裂。患者接受了腹腔镜右半肝切除术。术后病理分析诊断为肝并殖吸虫病。患者术后恢复良好,出院后给予 25mg/kg 吡喹酮口服,每日 3 次,共 3 天,疗效良好。在本病例中,肝肿块的破裂出血使得治疗医生难以考虑肝并殖吸虫病,导致了该患者的最初误诊。虽然并殖吸虫病非常罕见,但医务人员应保持警惕,全面了解可导致肝肿块的不同疾病,以避免误诊。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f3/8191090/103be454b77a/10.1177_03000605211012668-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f3/8191090/a0ae42daf7a0/10.1177_03000605211012668-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f3/8191090/103be454b77a/10.1177_03000605211012668-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f3/8191090/a0ae42daf7a0/10.1177_03000605211012668-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f3/8191090/103be454b77a/10.1177_03000605211012668-fig2.jpg

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本文引用的文献

1
Paragonimus and paragonimiasis in Asia: An update.亚洲的并殖吸虫和并殖吸虫病:最新进展。
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Hepatic paragonimiasis: a single-center retrospective analysis of 32 cases in Mainland China.肝吸虫病:中国大陆32例单中心回顾性分析
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3
Hepatic paragonimiasis in a 15-month-old girl: a case report.一名15个月大女童的肝肺吸虫病:病例报告
BMC Pediatr. 2017 Nov 15;17(1):190. doi: 10.1186/s12887-017-0942-5.
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Distinct MDCT imaging features to differential diagnosis of hepatic paragonimiasis and small hepatocellular carcinoma.多层螺旋CT(MDCT)成像在肝肺吸虫病与小肝细胞癌鉴别诊断中的独特特征
Oncotarget. 2017 Jun 6;8(23):37291-37295. doi: 10.18632/oncotarget.16197.
5
Feasibility of laparoscopic major hepatectomy for hepatic paragonimiasis: two case reports.腹腔镜下肝切除术治疗肝肺吸虫病的可行性:两例报告
Medicine (Baltimore). 2016 Sep;95(38):e4939. doi: 10.1097/MD.0000000000004939.
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Correlations between MDCT features and clinicopathological findings of hepatic paragonimiasis.肝并殖吸虫病 MDCT 特征与临床病理表现的相关性。
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