Stets V R, Dunaev V V, Mazur I A, Siniak R S
Farmakol Toksikol. 1988 May-Jun;51(3):67-9.
The effect of quinazopyrine on skin wound healing in rats was studied. Quinazopyrine was found to stimulate synthesis of nucleic acids, maturation of fibroblasts and to increase mechanical strength of the postoperative scar. This effect retains in animals with alloxan-induced diabetes. The wound-healing activity of quinazopyrine was higher than that of methyluracil, dimexide, pentoxyl, sodium nucleinate, potassium orotate and riboxine.
研究了喹唑啉对大鼠皮肤伤口愈合的影响。发现喹唑啉可刺激核酸合成、成纤维细胞成熟并增加术后瘢痕的机械强度。在四氧嘧啶诱导的糖尿病动物中这种作用依然存在。喹唑啉的伤口愈合活性高于甲基尿嘧啶、二甲亚砜、潘托昔康、核酸钠、乳清酸钾和核糖核酸。