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[二丁基羟基甲苯搽剂对小鼠创伤后皮肤再生的影响]

[Effect of dibunol liniment on posttraumatic skin regeneration in mice].

作者信息

Krutova T V, Efimov E A, Korman D B

出版信息

Biull Eksp Biol Med. 1984 Oct;98(10):471-3.

PMID:6498327
Abstract

The effect of dibunol liniment (5-50 mg/kg) on excised mouse skin was studied. The liniment caused complete skin regeneration with hair and gland formation in the majority of treated mice. Application of the liniment led to a considerable increase in proliferative activity of skin epithelial cells and inhibition of wound area reduction within the first day of healing as compared with controls.

摘要

研究了地布诺林搽剂(5 - 50毫克/千克)对切除的小鼠皮肤的影响。在大多数接受治疗的小鼠中,该搽剂使皮肤实现了完全再生,并伴有毛发和腺体形成。与对照组相比,涂抹该搽剂导致皮肤上皮细胞增殖活性显著增加,且在愈合的第一天抑制了伤口面积的缩小。

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