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[Prenatal effect of oleandomycin on the development of the immunogenesis organs].

作者信息

Petrova T B, Savitskaia T N

出版信息

Farmakol Toksikol. 1988 May-Jun;51(3):84-6.

PMID:3410038
Abstract

The ante- and postnatal development of the thymus gland and mesenteric lymph nodes of the rats receiving oleandomycin in the period of placentation and organogenesis (the 8th-14th days of embryogenesis) was studied by using anatomical, histological and electron microscopical methods. Oleandomycin produced inhibition of lymphopoiesis against the background of an increase of eosinophilic and neutrophilic granulocytes, reactive changes of the microcirculatory bed and ultrastructural lesions of the blood capillary wall.

摘要

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