Surgical Specialties, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia.
Department of Occupational Therapy, Royal Adelaide Hospital, Adelaide, SA, Australia.
JBI Evid Synth. 2021 Oct;19(10):2893-2903. doi: 10.11124/JBIES-20-00468.
The objective of this review is to examine the reliability and measurement error of devices that measure transepidermal water loss.
Transepidermal water loss is a physiological property of skin that increases when the epidermis is damaged. It is, therefore, a commonly utilized measure of skin barrier integrity. Devices measuring transepidermal water loss are available as open, semi-open, or closed chamber. Studies that examine the similarities and differences between transepidermal water loss measurement devices are available. However, there has not been a systematic review to comprehensively collate and critique these studies. The aim of this review will be to synthesize the data from these studies to aid in selection and use of transepidermal water loss measurement devices in clinical practice or research.
Studies examining the reliability and/or measurement error of transepidermal water loss measurement devices will be included. Studies that examine a single device to demonstrate how different handling affects measurements will also be included. Studies that only report on measurement of transepidermal water loss outcomes without examination of reliability and/or measurement error will be excluded.
The search strategy will aim to locate published and unpublished studies. Databases to be searched will include PubMed, Embase, CINAHL, and Web of Science, utilizing identified keywords and limited to studies in English. Gray literature sources will be searched to identify any unpublished documents. Study selection will adhere to the inclusion criteria and then be assessed by two reviewers for methodological quality utilizing COSMIN (COnsensus-based Standards for the selection of health status Measurement INstruments) guidelines and risk of bias tools. Extracted data will be presented in a narrative synthesis and as tables and figures to aid data presentation.
本次综述旨在检验测量经皮水分流失的装置的可靠性和测量误差。
经皮水分流失是皮肤的一种生理特性，当表皮受损时会增加。因此，它是一种常用于测量皮肤屏障完整性的方法。可测量经皮水分流失的装置有开放式、半开放式或密闭式室。已有研究检验了经皮水分流失测量装置之间的相似性和差异性。但是，目前还没有系统的综述来全面整理和评价这些研究。本次综述的目的是综合这些研究的数据，以帮助在临床实践或研究中选择和使用经皮水分流失测量装置。
将纳入检验经皮水分流失测量装置的可靠性和/或测量误差的研究。也将纳入检验单一装置以展示不同操作如何影响测量的研究。仅报告经皮水分流失结果而未检验可靠性和/或测量误差的研究将被排除。
检索策略旨在定位已发表和未发表的研究。将检索的数据库包括 PubMed、Embase、CINAHL 和 Web of Science，利用已确定的关键词，并将研究限制在英语中。将搜索灰色文献来源以确定任何未发表的文件。研究选择将遵循纳入标准，然后由两名评审员根据 COSMIN（健康状况测量仪器选择的共识标准）指南和偏倚风险工具评估方法学质量。提取的数据将以叙述性综合形式以及表格和图形呈现，以帮助数据呈现。
