School of Physical Therapy, Faculty of Health Sciences, Western University, London, Ontario, Canada
School of Physical Therapy, Faculty of Health Sciences, Western University, London, Ontario, Canada.
BMJ Open. 2022 Jun 6;12(6):e060950. doi: 10.1136/bmjopen-2022-060950.
Low back pain can lead to substantial decline in physical functioning. For disabling pain not responsive to conservative management, surgical intervention can enhance physical functioning. Measurements of physical functioning include patient-reported outcome measures and physical outcome measures using evaluations of impairments, performance on a standardised task or activity in a natural environment. Selecting outcome measures with adequate measurement properties is fundamental to evaluating effectiveness of interventions. The purpose of this systematic review is to identify outcome measures (patient reported and physical) used to evaluate physical functioning (stage 1) and assess the measurement properties of physical outcome measures of physical functioning (stage 2) in the lumbar spinal surgery population.
This protocol aligns with the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guidelines and Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols. Using a two-staged approach, searches will be performed in MEDLINE, EMBASE, Health and Psychosocial Instruments, CINAHL, Web of Science, Scopus, PEDro and the grey literature from inception until 15 December 2021. Stage 1 will identify studies evaluating physical functioning with patient-reported or physical outcome measures in the lumbar spinal surgery population. Stage 2 will search for studies evaluating measurement properties (validity, reliability, responsiveness) of the physical outcome measures identified in stage 1 in the lumbar spinal surgery population. Two independent reviewers will evaluate studies for inclusion, extract data, assess risk of bias (COSMIN risk of bias tool and checklist) and quality of evidence (modified Grading of Recommendations Assessment, Development and Evaluation approach). Results for each measurement property per physical outcome measure will be quantitatively pooled if there is adequate clinical and methodological homogeneity or qualitatively synthesised if there is high heterogeneity in studies.
Ethics approval is not required. Results will be disseminated through peer-reviewed journal publication and conference presentation.
CRD42021293880.
下腰痛可导致身体功能显著下降。对于保守治疗无效的致残性疼痛，手术干预可以增强身体功能。身体功能的测量包括患者报告的结果测量和使用损伤评估、在自然环境中的标准任务或活动中的表现来测量身体功能的身体结果测量。选择具有充分测量特性的结果测量是评估干预措施有效性的基础。本系统评价的目的是确定用于评估腰椎脊柱手术人群身体功能的（1 阶段）结果测量（患者报告和身体），并评估身体功能的身体结果测量的测量特性（2 阶段）。
本方案符合共识基础的健康测量仪器选择标准（COSMIN）指南和系统评价和荟萃分析方案的首选报告项目。使用两阶段方法，将在 MEDLINE、EMBASE、健康和社会心理仪器、CINAHL、Web of Science、Scopus、PEDro 和灰色文献中进行搜索，从开始到 2021 年 12 月 15 日。第 1 阶段将确定评估腰椎脊柱手术人群中患者报告或身体结果测量的身体功能的研究。第 2 阶段将搜索评估第 1 阶段在腰椎脊柱手术人群中确定的身体结果测量的测量特性（有效性、可靠性、反应性）的研究。两名独立的审查员将评估研究的纳入情况、提取数据、评估偏倚风险（COSMIN 偏倚风险工具和检查表）和证据质量（改良的推荐评估、制定和评估方法）。如果有足够的临床和方法学同质性，则对每个身体结果测量的每个测量特性进行定量汇总，如果研究存在高度异质性，则进行定性综合。
不需要伦理批准。结果将通过同行评审的期刊发表和会议报告进行传播。
PROSPERO 注册号：CRD42021293880。
