Carr M F, Ma J, Green P H
Department of Medicine, Columbia-Presbyterian Medical Center, New York, New York.
Gastroenterology. 1988 Oct;95(4):972-4. doi: 10.1016/0016-5085(88)90171-0.
Previous studies have suggested that Giardia lamblia may cause nonulcer dyspepsia as the sole manifestation of infection. To explore this premise, duodenal aspirates from patients undergoing upper endoscopy were examined for Giardia and results were correlated with endoscopic findings and symptoms. Of 155 patients, 15.5% had Giardia. Patients with dyspepsia, with or without obvious lesions at endoscopy, had a similar prevalence. Patients with vomiting and diarrhea had an increased prevalence (38.5%) (p less than 0.05). The prevalence of Giardia lamblia in this patient population is surprisingly high. This study suggests that Giardia lamblia infection is not a major cause of nonulcer dyspepsia.
先前的研究表明，蓝氏贾第鞭毛虫可能会导致非溃疡性消化不良，作为感染的唯一表现形式。为了探究这一前提，对上消化道内镜检查患者的十二指肠抽吸物进行了蓝氏贾第鞭毛虫检测，并将结果与内镜检查结果及症状相关联。在155例患者中，15.5%感染了蓝氏贾第鞭毛虫。有消化不良症状的患者，无论内镜检查时有无明显病变，患病率相似。有呕吐和腹泻症状的患者患病率增加（38.5%）（p小于0.05）。该患者群体中蓝氏贾第鞭毛虫的患病率出奇地高。这项研究表明，蓝氏贾第鞭毛虫感染并非非溃疡性消化不良的主要病因。
