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Enhancing prime editing by Csy4-mediated processing of pegRNA.

作者信息

Liu Yao, Yang Guang, Huang Shuhong, Li Xiangyang, Wang Xin, Li Guanglei, Chi Tian, Chen Yulin, Huang Xingxu, Wang Xiaolong

机构信息

Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.

School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

出版信息

Cell Res. 2021 Oct;31(10):1134-1136. doi: 10.1038/s41422-021-00520-x. Epub 2021 Jun 8.


DOI:10.1038/s41422-021-00520-x
PMID:34103663
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8486859/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1862/8486859/113b5b650d41/41422_2021_520_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1862/8486859/113b5b650d41/41422_2021_520_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1862/8486859/113b5b650d41/41422_2021_520_Fig1_HTML.jpg

相似文献

[1]
Enhancing prime editing by Csy4-mediated processing of pegRNA.

Cell Res. 2021-10

[2]
Broadening prime editing toolkits using RNA-Pol-II-driven engineered pegRNA.

Mol Ther. 2022-9-7

[3]
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Nat Biotechnol. 2022-2

[4]
Optimization of Prime Editing in Rice, Peanut, Chickpea, and Cowpea Protoplasts by Restoration of GFP Activity.

Int J Mol Sci. 2022-8-29

[5]
Multiplexed CRISPR/Cas9 Genome Editing and Gene Regulation Using Csy4 in Saccharomyces cerevisiae.

ACS Synth Biol. 2018-1-19

[6]
Development and Optimization of CRISPR Prime Editing System in Photoautotrophic Cells.

Molecules. 2022-3-8

[7]
Prime Editing in Mammals: The Next Generation of Precision Genome Editing.

CRISPR J. 2022-12

[8]
High-efficiency prime editing with optimized, paired pegRNAs in plants.

Nat Biotechnol. 2021-8

[9]
Prime editing-mediated correction of the leptin receptor in muscle cells of db/db mice.

Biotechnol J. 2024-5

[10]
Engineered pegRNAs improve prime editing efficiency.

Nat Biotechnol. 2022-3

引用本文的文献

[1]
CRISPR/Cas9 in colorectal cancer: Revolutionizing precision oncology through genome editing and targeted therapeutics.

Iran J Basic Med Sci. 2025

[2]
Genome Editing Breeding with CRISPR-Cas Nucleases, Base Editors, and Prime Editors.

Animals (Basel). 2025-7-22

[3]
CRISPR-based functional genomics tools in vertebrate models.

Exp Mol Med. 2025-7

[4]
Emerging trends in prime editing for precision genome editing.

Exp Mol Med. 2025-7

[5]
Emerging trends in transgene-free crop development: insights into genome editing and its regulatory overview.

Plant Mol Biol. 2025-7-9

[6]
Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations.

Adv Sci (Weinh). 2025-7

[7]
Systematic optimization of prime editing for enhanced efficiency and versatility in genome engineering across diverse cell types.

Front Cell Dev Biol. 2025-4-29

[8]
Current trends in gene therapy to treat inherited disorders of the brain.

Mol Ther. 2025-5-7

[9]
Recent advances in therapeutic gene-editing technologies.

Mol Ther. 2025-6-4

[10]
Prime Editing: A Revolutionary Technology for Precise Treatment of Genetic Disorders.

Cell Prolif. 2025-4

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