Paediatric Endocrinology Unit, Department of Paediatrics, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Nigeria.
Paediatric Endocrinology Unit, Department of Paediatrics, University of Nigeria, Ituku Ozalla Campus, Enugu, Nigeria.
Pan Afr Med J. 2021 Mar 9;38:250. doi: 10.11604/pamj.2021.38.250.19790. eCollection 2021.
diabetic complications have been identified as the major causes of morbidity and mortality in persons with type 1 diabetes mellitus (T1DM). Lack of appropriate glycaemic control is a significant risk factor for the onset and progression of long term complications of diabetes. Identifying the determinants of good glycaemic control is therefore imperative.
this was a cross-sectional, hospital-based study of children aged 3-18 years with T1DM. Subjects were consecutively enrolled after obtaining consent from their parents and assent from children aged ≥7 years. A questionnaire was completed recording their clinical history and sociodemographic variables. Their HbA1c was estimated and values ≤7.5% was defined as the cut-off for optimal glycaemic control.
seventy-one children with T1DM were enrolled for the study. Thirty-eight (53.5%) of them were males. Mean age (years) was 13.7±4. Mean age at onset of diabetes was 11.6 years (range: 3-16 years), mean duration of diabetes was 24.4 months (range: 4-84 months), mean HbA1c value was 10.5% (range: 6.4%-14%); a multivariate logistic regression analysis was performed to identify determinants of optimal glycaemic control. Only caregivers' involvement in diabetes management P<0.016, odd ratio 13.03 (95% CI: 1.60-105.95) was identified as determinant of good glycaemic control.
our data suggest that of all the sociodemographic factors studied, caregivers' involvement in diabetes management was the only strong determinant for optimal glycaemic control.
糖尿病并发症已被确定为 1 型糖尿病(T1DM)患者发病率和死亡率的主要原因。血糖控制不佳是糖尿病长期并发症发生和进展的一个重要危险因素。因此,确定良好血糖控制的决定因素是至关重要的。
这是一项横断面、基于医院的研究,纳入了年龄在 3-18 岁的 T1DM 儿童。在获得其父母同意和年龄≥7 岁的儿童同意后,连续纳入研究对象。完成一份问卷,记录他们的临床病史和社会人口统计学变量。估计他们的糖化血红蛋白(HbA1c)值,将≤7.5%定义为最佳血糖控制的截止值。
共有 71 名 T1DM 患儿纳入研究。其中 38 名(53.5%)为男性。平均年龄(岁)为 13.7±4。糖尿病发病年龄平均为 11.6 岁(范围:3-16 岁),糖尿病病程平均为 24.4 个月(范围:4-84 个月),平均 HbA1c 值为 10.5%(范围:6.4%-14%);进行了多变量逻辑回归分析,以确定最佳血糖控制的决定因素。只有照顾者参与糖尿病管理(P<0.016),比值比为 13.03(95%可信区间:1.60-105.95),被确定为良好血糖控制的决定因素。
我们的数据表明,在所研究的所有社会人口统计学因素中,照顾者参与糖尿病管理是最佳血糖控制的唯一重要决定因素。