Suppr超能文献

肺移植中的麻醉管理:我们的单中心经验。

Anesthetic management in lung transplantation: Our single-center experience.

作者信息

Erkılınç Atakan, Karaca Baysal Pınar, Gürcü Mustafa Emre

机构信息

Department of Anesthesiology and Reanimation, Kartal Koşuyolu High Specialization Education and Research Hospital, Istanbul, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2021 Apr 26;29(2):191-200. doi: 10.5606/tgkdc.dergisi.2021.9490. eCollection 2021 Apr.

Abstract

BACKGROUND

In this study, we aimed to discuss our anesthesia management strategies, experiences, and outcomes in patients undergoing lung transplantation.

METHODS

Between December 2016 and December 2018, a total of 53 patients (43 males, 10 females; mean age: 46.1±13 years; range, 14 to 64 years) undergoing lung transplantation in our center were included. The anesthesia technique, patients" characteristics, and perioperative clinical and follow-up data were recorded. The stage of lung disease was assessed using the New York Heart Association functional classification.

RESULTS

Two patients underwent single lung transplantation, while 51 patients underwent double lung transplantation. Idiopathic pulmonary fibrosis was the most common indication in 41.5% of the patients. All patients had end-stage lung disease (Class IV) and 79% were oxygen-dependent. The extracorporeal membrane oxygenation support was given to 32 patients.

CONCLUSION

The anesthetic management of lung transplantation is challenging, either due to the deterioration of the recipient"s physical performance and the complexity of the surgical techniques used. In general, a kind of mechanical support may be needed and extracorporeal membrane oxygenation is the first choice in the majority of patients. A close communication should be maintained between the surgeons, perfusion technicians, and anesthesiologists to ensure an optimal multidisciplinary approach and to achieve successful outcomes.

摘要

背景

在本研究中,我们旨在探讨肺移植患者的麻醉管理策略、经验及结果。

方法

纳入2016年12月至2018年12月期间在本中心接受肺移植的53例患者(43例男性,10例女性;平均年龄:46.1±13岁;范围14至64岁)。记录麻醉技术、患者特征以及围手术期临床和随访数据。采用纽约心脏协会功能分级评估肺部疾病阶段。

结果

2例患者接受单肺移植,51例患者接受双肺移植。特发性肺纤维化是41.5%患者最常见的适应证。所有患者均患有终末期肺部疾病(IV级),79%患者依赖吸氧。32例患者接受了体外膜肺氧合支持。

结论

由于受者身体状况恶化以及所采用手术技术的复杂性,肺移植的麻醉管理具有挑战性。一般来说,可能需要某种机械支持,体外膜肺氧合是大多数患者的首选。外科医生、灌注技师和麻醉医生之间应保持密切沟通,以确保采取最佳的多学科方法并取得成功结果。

相似文献

1
Anesthetic management in lung transplantation: Our single-center experience.
Turk Gogus Kalp Damar Cerrahisi Derg. 2021 Apr 26;29(2):191-200. doi: 10.5606/tgkdc.dergisi.2021.9490. eCollection 2021 Apr.
2
Anesthesia for Lung Transplantation.
Anesthesiol Clin. 2017 Sep;35(3):473-489. doi: 10.1016/j.anclin.2017.05.003. Epub 2017 Jul 5.
3
Extracorporeal membrane oxygenation as a bridge to lung transplantation: A single-center experience in the present era.
J Thorac Cardiovasc Surg. 2017 Nov;154(5):1798-1809. doi: 10.1016/j.jtcvs.2017.06.063. Epub 2017 Jul 31.
4
A Review of Anesthesia for Lung Transplantation.
J Chest Surg. 2022 Aug 5;55(4):293-300. doi: 10.5090/jcs.22.046.
6
Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation.
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1152-7. doi: 10.1016/j.jtcvs.2014.11.039. Epub 2014 Nov 21.
7
Extracorporeal membrane oxygenation as a bridge to pulmonary transplantation.
J Thorac Cardiovasc Surg. 2013 Mar;145(3):862-7; discussion 867-8. doi: 10.1016/j.jtcvs.2012.12.022. Epub 2013 Jan 11.
8
The Evolving Role of Extracorporeal Membrane Oxygenation in Lung Transplantation: Implications for Anesthetic Management.
J Cardiothorac Vasc Anesth. 2019 Jul;33(7):1995-2006. doi: 10.1053/j.jvca.2018.10.007. Epub 2018 Oct 10.
9
Anesthetic management of lung transplantation: impact of presenting disease.
Curr Opin Anaesthesiol. 2020 Feb;33(1):43-49. doi: 10.1097/ACO.0000000000000805.

引用本文的文献

1
Fluid management during pediatric lung transplantation: a single-center experience.
Transl Pediatr. 2025 May 30;14(5):881-892. doi: 10.21037/tp-2024-619. Epub 2025 May 27.
2
Intraoperative Circulatory Support in Lung Transplantation: Current Trend and Its Evidence.
Life (Basel). 2022 Jul 7;12(7):1005. doi: 10.3390/life12071005.

本文引用的文献

1
Intraoperative Anesthetic Management of Lung Transplantation: Center-Specific Practices and Geographic and Centers Size Differences.
J Cardiothorac Vasc Anesth. 2018 Feb;32(1):62-69. doi: 10.1053/j.jvca.2017.05.025. Epub 2017 May 17.
3
Anesthesia for Lung Transplantation.
Anesthesiol Clin. 2017 Sep;35(3):473-489. doi: 10.1016/j.anclin.2017.05.003. Epub 2017 Jul 5.
5
Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation.
J Thorac Cardiovasc Surg. 2015 Apr;149(4):1152-7. doi: 10.1016/j.jtcvs.2014.11.039. Epub 2014 Nov 21.
6
Outcomes of intraoperative venoarterial extracorporeal membrane oxygenation versus cardiopulmonary bypass during lung transplantation.
Ann Thorac Surg. 2014 Dec;98(6):1936-42; discussion 1942-3. doi: 10.1016/j.athoracsur.2014.06.072. Epub 2014 Oct 22.
7
The effects of anesthetic preconditioning with sevoflurane in an experimental lung autotransplant model in pigs.
Anesth Analg. 2011 Oct;113(4):742-8. doi: 10.1213/ANE.0b013e3182288e01. Epub 2011 Sep 2.
8
Should double lung transplant be performed with or without cardiopulmonary bypass?
Interact Cardiovasc Thorac Surg. 2011 May;12(5):799-804. doi: 10.1510/icvts.2010.263624. Epub 2011 Feb 5.
10
Intraoperative hemodynamic monitoring during organ transplantation: what is new?
Curr Opin Organ Transplant. 2009 Jun;14(3):291-6. doi: 10.1097/MOT.0b013e32832d927d.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验