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经尿道前列腺切除综合征所致肺水肿的成功治疗

Successful Treatment of Pulmonary Edema Caused by Transurethral Resection of the Prostate Syndrome.

作者信息

Tong Xuan Hung, Dinh Thi Thu Trang, Ngo Van Dinh, Nguyen Minh Ly

机构信息

Department of Anesthesiology and Pain Medicine - 108 Military Central Hospital, Hanoi, Vietnam.

出版信息

Res Rep Urol. 2021 Jun 1;13:297-301. doi: 10.2147/RRU.S288614. eCollection 2021.

Abstract

BACKGROUND

Transurethral resection of the prostate (TURP) syndrome is a complication of transurethral resection of the prostate procedure. The incidence of TURP syndrome ranges from 0.78% to 1.4%. This syndrome is caused by excessive absorption of electrolyte-free and hypotonic washing solution. The fluids absorb into the circulation, which leads to heart failure, hyponatremia, and a decrease in serum osmolality. Cerebral edema, coma, pulmonary edema, cardiovascular collapse, and even death are common complications.

CASE PRESENTATION

We report a patient who suffered severe TURP syndrome after transurethral resection of the prostate procedure. Clinical manifestations were pulmonary edema and respiratory failure. The concentration of Na was 112.6 mmol/l, which was severe hyponatremia. The serum osmolality pressure was 234mOsmol/kg, pH was 7.23, pO was 45mmHg and pCO was 44mmHg. The patient had successfully recovered after being used CPAP-PSV Pro breathing through a mask with + 5cmHO of PEEP, 8cmHO of supporting pressure, 70-100% of FiO, 20mg furosemide of intravenously, 150 mL of 3% NaCl, and 100mL natribicarbonate 8.4%.

CONCLUSION

TURP syndrome is a life-threatening complication of transurethral resection of the prostate procedure, which is caused by excessive absorption of electrolyte-free and hypotonic washing solution. Therefore, the patient should be monitored seriously, diagnosed early, and treated promptly.

摘要

背景

经尿道前列腺电切术(TURP)综合征是经尿道前列腺电切手术的一种并发症。TURP综合征的发生率在0.78%至1.4%之间。该综合征是由无电解质和低渗冲洗液的过度吸收引起的。液体吸收进入循环系统,导致心力衰竭、低钠血症和血清渗透压降低。脑水肿、昏迷、肺水肿、心血管衰竭甚至死亡是常见的并发症。

病例报告

我们报告了一例经尿道前列腺电切术后发生严重TURP综合征的患者。临床表现为肺水肿和呼吸衰竭。血钠浓度为112.6 mmol/l,属于严重低钠血症。血清渗透压为234mOsmol/kg,pH值为7.23,pO为45mmHg,pCO为44mmHg。通过面罩使用CPAP-PSV Pro模式呼吸,呼气末正压(PEEP)为+5cmH₂O,支持压力为8cmH₂O,吸入氧浓度(FiO₂)为70 - 100%,静脉注射20mg呋塞米,静脉滴注150 mL 3%氯化钠溶液和100mL 8.4%碳酸氢钠后,患者成功康复。

结论

TURP综合征是经尿道前列腺电切手术的一种危及生命的并发症,由无电解质和低渗冲洗液的过度吸收引起。因此,应对患者进行严密监测,早期诊断并及时治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/900b/8179823/6ec70f40af25/RRU-13-297-g0001.jpg

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