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[学习扩展新冠疫情下医用海洛因的处方模式]

[Learning to expand medical heroin prescribing modalities with Covid-19].

作者信息

Calzada Gerard, Giustiniani Julie, Gois Tiago, Kuntz André, Khazaal Yasser, Zullino Daniele

机构信息

Service d'addictologie, Département de psychiatrie, HUG, 1211 Genève 14.

Centre cantonal d'addictologie, Réseau fribourgeois de santé mentale, rue de Morat 8, 1700 Fribourg.

出版信息

Rev Med Suisse. 2021 Jun 9;17(742):1111-1114.

PMID:34106535
Abstract

The choice of opioid-assisted treatments for patients with heroin dependence is particularly diverse in Switzerland. Since 1994, diacetylmorphine assisted treatments are available. The rules for prescribing and dispensing diacetylmorphine, as laid down by the FOPH, are particularly strict, requiring patients to attend the treatment center several times a day. Thanks to a legislative amendment by the Federal Council, it became possible to extend the dispensing of diacetylmorphine during the Covid-19 epidemic, allowing patients to take the treatment with them for longer periods and thus reducing the number of visits to the clinic. The time freed up could then be invested in other activities, allowing therapies to be refocused more on the patients' life project.

摘要

在瑞士,针对海洛因依赖患者的阿片类药物辅助治疗选择尤为多样。自1994年起,可提供二乙酰吗啡辅助治疗。瑞士公共卫生署制定的二乙酰吗啡处方和配药规则特别严格,要求患者每天多次前往治疗中心。由于联邦委员会的一项立法修正案,在新冠疫情期间可以延长二乙酰吗啡的配药期限,使患者能够携带药物进行更长时间的治疗,从而减少前往诊所的次数。这样腾出来的时间就可以投入到其他活动中,使治疗能够更多地围绕患者的生活规划进行调整。

相似文献

1
[Learning to expand medical heroin prescribing modalities with Covid-19].[学习扩展新冠疫情下医用海洛因的处方模式]
Rev Med Suisse. 2021 Jun 9;17(742):1111-1114.
2
Experiences with take-home dosing in heroin-assisted treatment in Switzerland during the COVID-19 pandemic-Is an update of legal restrictions warranted?在 COVID-19 大流行期间,瑞士海洛因辅助治疗的带药回家治疗经验-是否有必要更新法律限制?
Int J Drug Policy. 2022 Mar;101:103548. doi: 10.1016/j.drugpo.2021.103548. Epub 2021 Nov 26.
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Prolonged diacetylmorphine take-home during the COVID-19 pandemic-Results of a retrospective cohort study.COVID-19 大流行期间延长携带二乙酰吗啡-回顾性队列研究结果。
Addiction. 2024 Aug;119(8):1421-1429. doi: 10.1111/add.16503. Epub 2024 Apr 21.
4
Nasal administration of diacetylmorphine improved the adherence in a patient receiving heroin-assisted treatment.经鼻给予二乙酰吗啡可提高接受海洛因维持治疗患者的依从性。
Harm Reduct J. 2022 Jun 7;19(1):63. doi: 10.1186/s12954-022-00644-2.
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Hydromorphone Compared With Diacetylmorphine for Long-term Opioid Dependence: A Randomized Clinical Trial.氢吗啡酮与二乙酰吗啡治疗长期阿片类药物依赖的随机临床试验。
JAMA Psychiatry. 2016 May 1;73(5):447-55. doi: 10.1001/jamapsychiatry.2016.0109.
6
Arterial and venous pharmacokinetics of intravenous heroin in subjects who are addicted to narcotics.对麻醉品成瘾者静脉注射海洛因后的动静脉药代动力学研究。
Clin Pharmacol Ther. 2001 Sep;70(3):237-46. doi: 10.1067/mcp.2001.117981.
7
Oral diacetylmorphine (heroin) yields greater morphine bioavailability than oral morphine: bioavailability related to dosage and prior opioid exposure.口服二乙酰吗啡(海洛因)比口服吗啡产生更高的吗啡生物利用度:生物利用度与剂量及先前的阿片类药物暴露有关。
Br J Clin Pharmacol. 2008 Dec;66(6):781-91. doi: 10.1111/j.1365-2125.2008.03286.x.
8
Take home injectable opioids for opioid use disorder during and after the COVID-19 Pandemic is in urgent need: a case study.COVID-19大流行期间及之后用于阿片类物质使用障碍的居家注射用阿片类药物亟待解决:一项案例研究
Subst Abuse Treat Prev Policy. 2021 Mar 5;16(1):22. doi: 10.1186/s13011-021-00358-x.
9
Medical prescription of heroin to chronic heroin addicts in Switzerland - a review.瑞士针对慢性海洛因成瘾者的海洛因医疗处方——一项综述
Forensic Sci Int. 2001 Sep 15;121(1-2):23-6. doi: 10.1016/s0379-0738(01)00448-0.
10
Safety profile of injectable hydromorphone and diacetylmorphine for long-term severe opioid use disorder.注射用氢吗啡酮和二乙酰吗啡用于长期重度阿片类药物使用障碍的安全性概况。
Drug Alcohol Depend. 2017 Jul 1;176:55-62. doi: 10.1016/j.drugalcdep.2017.02.021. Epub 2017 May 10.