University of Nebraska Medical Center, Omaha, Nebraska.
University of Calgary, Arnie Charbonneau Cancer Research Institute, Calgary, Alberta, Canada.
Transplant Cell Ther. 2021 Oct;27(10):807-816. doi: 10.1016/j.jtct.2021.05.027. Epub 2021 Jun 6.
The fifth annual Blood and Marrow Transplant Clinical Trials Network Myeloma Intergroup Workshop on Immune Profiling and Minimal Residual Disease Testing in Multiple Myeloma was conducted as one of the American Society of Hematology Annual Meeting Scientific Workshops on Thursday December 3, 2020. This workshop focused on four main topics: (1) integrating minimal residual disease into clinical trial design and practice; (2) the molecular and immunobiology of disease evolution and progression in myeloma; (3) adaptation of next-generation sequencing, next-generation flow cytometry, and cytometry by time of flight techniques; and (4) chimeric antigen receptor T-cell and other cellular therapies for myeloma. In this report, we provide a summary of the workshop presentations and discuss future directions in the field.
第五届血液和骨髓移植临床研究网络多发性骨髓瘤免疫组化和微小残留病灶检测年度研讨会作为 2020 年 12 月 3 日星期四美国血液学会年会科学研讨会之一举行。本次研讨会重点讨论了四个主要主题：（1）将微小残留病灶纳入临床试验设计和实践；（2）骨髓瘤疾病演变和进展的分子和免疫生物学；（3）下一代测序、下一代流式细胞术和飞行时间技术的应用；（4）嵌合抗原受体 T 细胞和其他用于多发性骨髓瘤的细胞疗法。在本报告中，我们提供了研讨会报告的摘要，并讨论了该领域的未来发展方向。
