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驹腹泻的流行病学调查

Epidemiologic survey of diarrhea in foals.

作者信息

Traub-Dargatz J L, Gay C C, Evermann J F, Ward A C, Zeglen M E, Gallina A M, Salman M D

机构信息

Department of Clinical Sciences, Washington State University, Pullman 99164.

出版信息

J Am Vet Med Assoc. 1988 Jun 1;192(11):1553-6.

PMID:3410771
Abstract

Epidemiologic and etiologic data about diarrhea in foals were collected under a planned prospective recording and monitoring study. The survey and monitoring procedures included a survey to obtain an overview of current horse management practices on participating farms, a daily health record survey to obtain information on mares and their foals, and collection of feces from 19 of 144 diarrheic foals and 10 age-matched nondiarrheic foals for electron microscopy, ELISA for rotavirus, and bacteriologic culture. Coronavirus was detected in the feces of diarrheic as well as clinically normal foals. Rotavirus was detected in the feces of diarrheic foals only. With regard to agents found in the feces, there was no significant (P less than 0.05) difference between diarrheic and nondiarrheic foals. Half of the 297 foals on which data were available developed diarrhea. Most foals that developed diarrhea lacked other clinical manifestations of disease. Basic cleanliness at foaling was associated with a lower percentage of foals developing diarrhea. Prophylactic use of antibiotics and vitamins in newborn foals was associated with a higher percentage of foals developing diarrhea. A higher percentage of foals born to visiting mares developed diarrhea, compared with foals born to resident mares.

摘要

在一项有计划的前瞻性记录与监测研究中,收集了有关幼驹腹泻的流行病学和病因学数据。调查与监测程序包括一项用以全面了解参与研究农场当前马匹管理做法的调查、一项每日健康记录调查以获取有关母马及其幼驹的信息,以及从144匹腹泻幼驹中的19匹和10匹年龄匹配的非腹泻幼驹中采集粪便用于电子显微镜检查、轮状病毒酶联免疫吸附测定(ELISA)和细菌培养。在腹泻幼驹以及临床正常幼驹的粪便中均检测到冠状病毒。仅在腹泻幼驹的粪便中检测到轮状病毒。就粪便中发现的病原体而言,腹泻幼驹与非腹泻幼驹之间无显著(P小于0.05)差异。有数据可查的297匹幼驹中有一半发生了腹泻。大多数发生腹泻的幼驹缺乏疾病的其他临床表现。产驹时的基本清洁状况与发生腹泻的幼驹比例较低相关。新生幼驹预防性使用抗生素和维生素与发生腹泻的幼驹比例较高相关。与常住母马所生幼驹相比,外来母马所生幼驹发生腹泻的比例更高。

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