Suppr超能文献

潜在可避免的儿童死亡与中低收入国家手术人员规模扩大相关:一项全球研究。

Potentially Avertable Child Mortality Associated with Surgical Workforce Scale-up in Low- and Middle-Income Countries: A Global Study.

机构信息

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.

Division of Pediatric Surgery, Hospital das Clínicas, UFMG, Belo Horizonte, Minas Gerais, Brazil.

出版信息

World J Surg. 2021 Sep;45(9):2643-2652. doi: 10.1007/s00268-021-06181-6. Epub 2021 Jun 10.

Abstract

BACKGROUND

Expansion of access to surgical care can improve health outcomes, although the impact that scale-up of the surgical workforce will have on child mortality is poorly defined. In this study, we estimate the number of child deaths potentially avertable by increasing the surgical workforce globally to meet targets proposed by the Lancet Commission on Global Surgery.

METHODS

To estimate the number of deaths potentially avertable through increases in the surgical workforce, we used log-linear regression to model the association between surgeon, anesthetist and obstetrician workforce (SAO) density and surgically amenable under-5 mortality rate (U5MR), infant mortality rate (IMR), and neonatal mortality rate (NMR) for 192 countries adjusting for potential confounders of childhood mortality, including the non-surgical workforce (physicians, nurses/midwives, community health workers), gross national income per capita, poverty rate, female literacy rate, health expenditure per capita, percentage of urban population, number of surgical operations, and hospital bed density. Surgically amenable mortality was determined using mortality estimates from the UN Inter-agency Group for Child Mortality Estimation adjusted by the proportion of deaths in each country due to communicable causes unlikely to be amenable to surgical care. Estimates of mortality reduction due to upscaling surgical care to support the Lancet Commission on Global Surgery (LCoGS) minimum target of 20-40 SAO/100,000 were calculated accounting for potential increases in surgical volume associated with surgical workforce expansion.

RESULTS

Increasing SAO workforce density was independently associated with lower surgically amenable U5MR as well as NMR (p < 0.01 for each model). When accounting for concomitant increases in surgical volume, scale-up of the surgical workforce to 20-40 SAO/100,000 could potentially prevent between 262,709 (95% CI 229,643-295,434) and 519,629 (465,046-573,919) under 5 deaths annually. The majority (61%) of deaths averted would be neonatal deaths.

CONCLUSION

Scale up of surgical workforce may substantially decrease childhood mortality rates around the world. Our analysis suggests that scale-up of surgical delivery through increase in the SAO workforce could prevent over 500,000 children from dying before the age of 5 annually. This would represent significant progress toward meeting global child mortality reduction targets.

摘要

背景

扩大获得外科护理的机会可以改善健康结果,尽管扩大外科劳动力规模对儿童死亡率的影响尚未得到明确界定。在这项研究中,我们估计通过增加全球外科劳动力数量来满足柳叶刀全球外科委员会提出的目标,从而避免的儿童死亡人数。

方法

为了估计通过增加外科劳动力数量而避免的死亡人数,我们使用对数线性回归来模拟外科医生、麻醉师和产科医生人数(SAO)密度与可手术治疗的 5 岁以下儿童死亡率(U5MR)、婴儿死亡率(IMR)和新生儿死亡率(NMR)之间的关联,为 192 个国家调整了儿童死亡率的潜在混杂因素,包括非外科劳动力(医生、护士/助产士、社区卫生工作者)、人均国民总收入、贫困率、女性识字率、人均卫生支出、城市人口比例、手术数量和床位密度。可手术治疗的死亡率是根据联合国机构间儿童死亡率估计小组的死亡率估计数确定的,这些死亡率数经过了每个国家因可能无法接受手术治疗的传染病导致的死亡比例的调整。通过扩大外科护理来支持柳叶刀全球外科委员会(LCoGS)最低目标 20-40 SAO/100,000 来估算死亡率降低的估计数,同时考虑了与外科劳动力扩张相关的手术量的潜在增加。

结果

SAO 劳动力密度的增加与可手术治疗的 U5MR 以及 NMR 呈负相关(每个模型均为 p < 0.01)。在考虑到手术量的同时增加时,将外科劳动力扩大到 20-40 SAO/100,000 每年可潜在预防 262709(95%CI 229643-295434)至 519629(465046-573919)例 5 岁以下儿童死亡。避免的死亡人数中有 61%(新生儿死亡)。

结论

扩大外科劳动力规模可能会大大降低全球儿童死亡率。我们的分析表明,通过增加 SAO 劳动力数量来扩大外科服务的提供,可以防止每年有超过 50 万儿童在 5 岁之前死亡。这将是朝着实现全球儿童死亡率降低目标迈出的重要一步。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验