Substance Use, Gender, and Applied Research Program, RTI International, Research Triangle Park, NC, USA.
Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.
Curr HIV/AIDS Rep. 2021 Aug;18(4):351-364. doi: 10.1007/s11904-021-00558-x. Epub 2021 Jun 10.
Alcohol is the most misused substance in the world. For people living with HIV (PLWH), alcohol misuse may impact ART adherence and viral suppression. This review of the most recently published alcohol intervention studies with PLWH examines how these studies considered gender in the samples, design, and analyses.
Three searches were conducted initially, and 13 intervention studies fit our criteria with alcohol outcomes. In general, most studies did not consider gender and had used small samples, and few demonstrated significant efficacy/effectiveness outcomes. Five studies considered gender in their samples or analyses and/or were woman-focused with larger samples and demonstrated significant outcomes. It is essential for women who misuse alcohol to not only be well represented in alcohol and HIV research but also for studies to consider the barriers to reaching them and their contextual demands and/or co-occurring issues that may affect participation and outcomes in intervention research.
酒精是世界上使用最广泛的物质。对于感染人类免疫缺陷病毒(HIV)的人群(PLWH),酒精滥用可能会影响抗逆转录病毒治疗(ART)的依从性和病毒抑制。本综述对最近发表的 PLWH 酒精干预研究进行了回顾,探讨了这些研究在样本、设计和分析中是如何考虑性别的。
最初进行了三次搜索,符合我们标准并具有酒精结果的干预研究有 13 项。总的来说,大多数研究没有考虑性别,样本量较小,很少有研究显示出显著的疗效/效果结果。有五篇研究考虑了样本或分析中的性别,或者是以女性为重点,样本量较大,结果显著。酒精滥用的女性不仅需要在酒精和 HIV 研究中得到充分的代表性,而且研究还需要考虑到接触这些女性的障碍以及她们的环境需求和/或共同存在的问题,这些问题可能会影响干预研究的参与和结果。