Miyagoshi M, Amagaya S, Ogihara Y
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.
J Pharmacobiodyn. 1988 Mar;11(3):186-90. doi: 10.1248/bpb1978.11.186.
The intravenous administration of 50 and 100 mg/kg of genipin (GP), gardenogenins (GAR-G), deacetylasperulosidic acid methylester genins (DAM-G), and scandoside methylester genin (SSM-G) exhibited the bile acid-independent choleretic actions. The action of DAM-G was stronger than the actions of other compounds tested. The choleretic action of SSM-G was milder, but longer lasting than those of GAR-G and DAM-G.
静脉注射50毫克/千克和100毫克/千克的京尼平（GP）、栀子苷元（GAR-G）、去乙酰车叶草苷酸甲酯苷元（DAM-G）和 scandoside 甲酯苷元（SSM-G）均表现出不依赖胆汁酸的利胆作用。DAM-G的作用强于其他受试化合物。SSM-G的利胆作用较温和，但比GAR-G和DAM-G的作用持续时间更长。
