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[可摘矫治器中闪光颗粒的铝释放]

[Aluminium release of glitter particles in removable orthodontic appliances].

作者信息

Wepner Lena, Färber Harald Andreas, Weber Anna, Jaensch Andreas, Keilig Ludger, Heuser Florian Andreas, Bourauel Christoph Peter

机构信息

Oralmedizinische Technologie, Zentrum für Zahn‑, Mund- und Kieferheilkunde, Medizinische Fakultät, Universitätsklinikum Bonn (AöR), Universität Bonn, Bonn, Deutschland.

Institut für Hygiene und öffentliche Gesundheit, Medizinische Fakultät, Universitätsklinikum Bonn (AöR), Universität Bonn, Venusberg-Campus 1 (Gebäude 63), 53127, Bonn, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Jul;64(7):856-861. doi: 10.1007/s00103-021-03361-6. Epub 2021 Jun 11.

Abstract

BACKGROUND AND AIM

In order to support children's compliance with orthodontic treatment, glitter particles containing aluminium (Al) are often embedded in the acrylic of removable appliances. When worn for up to 16 h daily for 2-3 years, it can be assumed that Al ions diffuse into saliva over time. The aim of this study was to investigate the release of Al ions from the acrylic using different orthodontic wires.

MATERIALS AND METHOD

Test specimens (surface area 5.65 cm) were prepared from orthodontic resin and various wires; half contained aluminium glitter particles. The test specimens were placed in Petri dishes containing 50 ml of corrosion medium (pH 2.3) according to DIN EN ISO 10271 at 37 °C for 7 days. Inductively coupled plasma mass spectrometry (ICP-MS) was used to quantify the specific ions in the corrosion solution.

RESULTS

Statistical analysis showed a significant difference in the concentration of Al ions between samples with and without glitter particles. Concentrations from samples with glitter reached up to 14,474 μg/l Al ions; samples without glitter contained on average 1260 μg/l. A small proportion of the Al ions may originate from the alloys of the wires.

CONCLUSIONS

It should be investigated whether the aluminium concentration can lead to health risks for humans. In view of the findings, orthodontists should not offer appliances containing glitter in order to minimize aluminium uptake with saliva. It needs to be clarified whether the conditions found in the oral cavity lead to the same results as under the abovementioned conditions. Legislation should be developed to limit the release of aluminium from orthodontic products.

摘要

背景与目的

为了促使儿童配合正畸治疗,含铝的亮片颗粒常被嵌入可摘矫治器的丙烯酸树脂中。当每天佩戴长达16小时,持续2至3年时,可以推测铝离子会随着时间扩散到唾液中。本研究的目的是调查使用不同正畸钢丝时丙烯酸树脂中铝离子的释放情况。

材料与方法

从正畸树脂和各种钢丝制备测试样本(表面积5.65平方厘米);其中一半含有铝亮片颗粒。根据DIN EN ISO 10271标准,将测试样本置于含有50毫升腐蚀介质(pH 2.3)的培养皿中,在37°C下放置7天。使用电感耦合等离子体质谱法(ICP-MS)对腐蚀溶液中的特定离子进行定量分析。

结果

统计分析表明,含亮片颗粒和不含亮片颗粒样本中铝离子浓度存在显著差异。含亮片样本中的铝离子浓度高达14474μg/l;不含亮片的样本平均含有1260μg/l。一小部分铝离子可能源自钢丝的合金。

结论

应调查铝浓度是否会对人体健康造成风险。鉴于研究结果,正畸医生不应提供含亮片的矫治器,以尽量减少唾液对铝的摄取。口腔内的条件是否会导致与上述条件相同的结果尚需阐明。应制定法规限制正畸产品中铝的释放。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84f0/8241636/c42aefe5eee0/103_2021_3361_Fig1_HTML.jpg

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