Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India.
Int J Clin Pract. 2021 Sep;75(9):e14494. doi: 10.1111/ijcp.14494. Epub 2021 Jun 22.
The primary objective of this article is to understand the various complications caused by the coronavirus in the paediatric population.
An electronic search was conducted using PubMed and incorporated forward and backward research methods on clinical trials, case reports, case series, guidelines and reports from the centre for disease control and prevention (CDC), and the keywords included COVID-19, paediatrics, multisystem inflammatory syndrome in children (MIS-C), complications, acute kidney injury and heart failure. Secondary resources included one study from preprint servers (www.preprints.org), last search 8 May 2021, with notion of nonpeer review status. Data were collected and analysed to stay current with the most recent alerts and guidelines for the best care for children during the COVID-19 pandemic.
Evaluation and analysis of literature revealed MIS-C to be the most prevalent followed by neurological complications. Whereas the least prevalent were septic shock and ophthalmic complications.
Even though COVID-19 is known to be a less severe in the paediatric population, the complications of the virus have caused a great deal of stress to the paediatric patients' parents and paediatricians worldwide, and hence, emphasis should be given to the management of coronavirus complications in paediatrics.
本文的主要目的是了解冠状病毒在儿科人群中引起的各种并发症。
使用 PubMed 进行电子检索,并结合临床试验、病例报告、病例系列、疾病控制和预防中心 (CDC) 的指南和报告的前瞻性和回顾性研究方法,关键词包括 COVID-19、儿科、儿童多系统炎症综合征 (MIS-C)、并发症、急性肾损伤和心力衰竭。次要资源包括来自预印本服务器(www.preprints.org)的一项研究,最后一次搜索是在 2021 年 5 月 8 日,具有非同行评审状态的概念。收集和分析数据以了解有关 COVID-19 大流行期间儿童最佳护理的最新警报和指南。
对文献的评估和分析表明,MIS-C 是最常见的,其次是神经系统并发症。而败血症性休克和眼部并发症则较少见。
尽管众所周知 COVID-19 在儿科人群中较轻,但该病毒的并发症给全世界儿科患者的父母和儿科医生带来了很大压力,因此,应重视儿童冠状病毒并发症的管理。