College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Int J Biol Macromol. 2021 Aug 1;184:9-19. doi: 10.1016/j.ijbiomac.2021.06.037. Epub 2021 Jun 8.
Inspired by biomaterials with hard and soft structures, we reported a type of self-healed, recyclable and antimicrobial elastomers material (ECTS) which exhibited both strong mechanical strength and high toughness. ECTS was designed by furfuryl amine modified epoxy natural rubber (ENR-FA) and furaldehyde modified chitosan (CTS-FUR) through Diels-Alder (D-A) reaction. The dynamic loading capacity of the chitosan skeleton, the stress ductility of the matrix and the dynamic cross-linking between the hard and soft components gave the elastomer excellent mechanical strength, toughness and self-healing ability. The tensile strength and the elongation at break could reach up to 7.55 MPa and 487%, respectively. In addition, due to the reversibility of the covalent bond between chitosan framework and rubber matrix, the crosslinking network destroyed by external force could be reestablished under high temperature stimulation. The mechanical properties of the sample could be restored to more than 90% of the original sample, whether it was complete fracture, cyclic damage or recyclable. ECTS exhibited excellent antibacterial activity against both gram-positive bacteria (Staphylococcus aureus) and gram-negative bacteria (Pseudomonas aeruginosa), with antibacterial efficiency more than 99%. So, ECTS might has a promising application prospect in medical materials, intelligent devices, 4D-printing, etc.
受硬软结构生物材料的启发，我们报道了一种自修复、可回收和抗微生物的弹性体材料（ECTS），它具有高强度和高韧性。ECTS 通过 Diels-Alder（D-A）反应由糠胺改性环氧树脂天然橡胶（ENR-FA）和糠醛改性壳聚糖（CTS-FUR）设计而成。壳聚糖骨架的动态承载能力、基体的应力延展性以及硬软组分之间的动态交联赋予了弹性体优异的机械强度、韧性和自修复能力。拉伸强度和断裂伸长率分别高达 7.55 MPa 和 487%。此外，由于壳聚糖骨架和橡胶基体之间的共价键具有可逆性，在外力破坏交联网络的情况下，在高温刺激下可以重新建立交联网络。无论是完全断裂、循环损伤还是可回收性，样品的力学性能都可以恢复到原始样品的 90%以上。ECTS 对革兰氏阳性菌（金黄色葡萄球菌）和革兰氏阴性菌（铜绿假单胞菌）均表现出优异的抗菌活性，抗菌效率超过 99%。因此，ECTS 在医用材料、智能设备、4D 打印等领域可能具有广阔的应用前景。
