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2019冠状病毒病(COVID-19)重症孕妇管理中的伦理挑战

Ethical challenges in management of critically ill pregnant patients with coronavirus disease 2019 (COVID-19).

作者信息

Gulersen Moti, Rochelson Burton, Bornstein Eran, McCullough Laurence B, Chervenak Frank A

机构信息

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, North Shore University Hospital - Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, USA.

Department of Obstetrics and Gynecology, Lenox Hill Hospital - Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.

出版信息

J Perinat Med. 2021 Jun 11. doi: 10.1515/jpm-2021-0254.

Abstract

Despite the overwhelming number of coronavirus disease 2019 (COVID-19) cases worldwide, data regarding the optimal clinical guidance in pregnant patients is not uniform or well established. As a result, clinical decisions to optimize maternal and fetal benefit, particularly in patients with critical COVID-19 in the early preterm period, continue to be a challenge for obstetricians. There is often uncertainty in clinical judgment about fetal monitoring, timing of delivery, and mode of delivery because of the challenge in balancing maternal and fetal interests in reducing morbidity and mortality. The obstetrician and critical care team should empower pregnant patients or their surrogate decision maker to make informed decisions in response to the team's clinical evaluation. A clinically grounded ethical framework, based on the concepts of the moral management of medical uncertainty, beneficence-based obligations, and preventive ethics, should guide the decision-making process.

摘要

尽管全球范围内2019冠状病毒病(COVID-19)病例数量众多,但关于孕妇最佳临床指导的数据并不统一,也未得到充分确立。因此,优化母婴获益的临床决策,尤其是对于早期早产且患有重症COVID-19的患者,仍然是产科医生面临的一项挑战。由于在平衡母婴利益以降低发病率和死亡率方面存在挑战,临床判断在胎儿监测、分娩时机和分娩方式等方面往往存在不确定性。产科医生和重症护理团队应赋予孕妇或其替代决策者权力,使其能够根据团队的临床评估做出明智的决策。一个基于医学不确定性的道德管理、基于行善义务和预防伦理概念的临床伦理框架,应指导决策过程。

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