当前和新型的多模态成像技术评估视网膜氧合和血流。
Current and novel multi-imaging modalities to assess retinal oxygenation and blood flow.
机构信息
Department of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Retina Division, The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
出版信息
Eye (Lond). 2021 Nov;35(11):2962-2972. doi: 10.1038/s41433-021-01570-6. Epub 2021 Jun 11.
Retinal ischemia characterizes the underlying pathology in a multitude of retinal diseases that can ultimately lead to vision loss. A variety of novel imaging modalities have been developed to characterize retinal ischemia by measuring retinal oxygenation and blood flow in-vivo. These technologies offer valuable insight into the earliest pathophysiologic changes within the retina and provide physicians and researchers with new diagnostic and monitoring capabilities. Future retinal imaging technologies with the capability to provide affordable, noninvasive, and comprehensive data on oxygen saturation, vasculature, and blood flow mechanics are needed. This review will highlight current and future trends in multimodal imaging to assess retinal blood flow and oxygenation.
视网膜缺血是多种视网膜疾病的基础病理特征，最终可导致视力丧失。为了在体内测量视网膜氧合和血流，已经开发出多种新型成像方式来对视网膜缺血进行特征描述。这些技术为了解视网膜内最早的病理生理变化提供了有价值的信息，并为医生和研究人员提供了新的诊断和监测能力。未来需要具有提供负担得起、无创和全面的氧饱和度、血管和血流力学数据的视网膜成像技术。本文将重点介绍评估视网膜血流和氧合的多模态成像的当前和未来趋势。
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