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新冠病毒感染后反应性关节炎:两例儿科病例简要报告。

Post SARS-CoV-2 infection reactive arthritis: a brief report of two pediatric cases.

机构信息

Department of Pediatrics, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Pediatr Rheumatol Online J. 2021 Jun 12;19(1):89. doi: 10.1186/s12969-021-00555-9.

Abstract

BACKGROUND

Although, preliminary reports of Severe Acute Respiratory Syndrome (SARS)-CoV-2 infection suggest that the infection causes a less severe illness in children, there is now growing evidence of other rare or even serious complications of disease.

CASE PRESENTATION

During the recent COVID-19 pandemic in Kerman, Iran, two children (an 8 year-old boy and a 6 year-old girl) were referred to outpatient Clinic of Pediatric Rheumatology with complaints of limping. Both children had experienced fever and mild respiratory tract infection. At the beginning of the second week of infection, they developed joint effusion. They both tested positive for coronavirus infection and were therefore diagnosed with post Coronavirus reactive arthritis. Both children were treated successfully with rest and Non-Steroidal Anti-Inflammatory Drugs (NSAID). They did not have any medical problems in the two months fallow up.

CONCLUSIONS

These two cases suggest that COVID-19 may be rheumatogenic. Highlighting the need for awareness of physicians, especially pediatricians, regarding the pathogenesis margins of this virus, as late presentations are of great importance.

摘要

背景

尽管初步报告表明,儿童感染严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)的症状较轻,但现在越来越多的证据表明,这种疾病还会导致其他罕见甚至严重的并发症。

病例介绍

在伊朗克尔曼省最近的 COVID-19 大流行期间,两名儿童(一名 8 岁男孩和一名 6 岁女孩)因跛行被转诊至儿科风湿病门诊。两名儿童均有发热和轻度呼吸道感染史。在感染的第二周初,他们出现关节积液。他们均被检测出冠状病毒感染呈阳性,因此被诊断为新冠病毒感染后反应性关节炎。两名儿童均成功接受休息和非甾体抗炎药(NSAID)治疗。在接下来的两个月随访中,他们没有出现任何其他健康问题。

结论

这两个病例表明 COVID-19 可能具有致关节炎性。这凸显了医生,尤其是儿科医生对此病毒发病机制范围的认识的必要性,因为晚期表现非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5932/8196509/7662e620a3e8/12969_2021_555_Fig1_HTML.jpg

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