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COVID-19 后反应性关节炎:基于病例的综述。

Reactive arthritis after COVID-19: a case-based review.

机构信息

Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Kahramanmaraş Sütçü İmam University, Kahramanmaraş, Turkey.

Physiotherapy and Rehabilitation Application and Research Center, Hasan Kalyoncu University, Gaziantep, Turkey.

出版信息

Rheumatol Int. 2021 Nov;41(11):2031-2039. doi: 10.1007/s00296-021-04998-x. Epub 2021 Sep 22.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the coronavirus disease 19 (COVID-19) pandemic, which is deeply affecting the whole world. In this new case for the scientific world, scientists are investigating the etiopathogenesis of viral infection-induced damage and have started to focus on the short and long-term immune system effects and alterations after SARS-CoV-2 infection. The case is here reported of a 53-year-old female patient with acute monoarthritis after SARS-CoV-2 infection, who responded adequately to 150 mg/day diclofenac treatment, and the available case reports are comprehensively reviewed. With the focus on arthritis after SARS-CoV2 infection, which emerges as a new pathological condition associated with COVID-19, it was aimed to examine the possible immunological mechanisms of post-COVID-19 arthritis based on the current data on SARS-CoV-2 and the known pathogenetic background of viral arthritis.

摘要

严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)是导致 19 冠状病毒病(COVID-19)大流行的病原体,它正在深刻影响整个世界。在这一科学领域的新案例中,科学家们正在研究病毒感染诱导的损伤的病因发病机制,并开始关注 SARS-CoV-2 感染后的短期和长期免疫系统效应和改变。本文报告了一例 53 岁女性患者在 SARS-CoV-2 感染后发生急性单关节炎,她对 150mg/天双氯芬酸治疗反应良好,并对现有病例报告进行了全面复习。本研究聚焦于 SARS-CoV2 感染后出现的关节炎,这是一种与 COVID-19 相关的新病理状况,目的是根据 SARS-CoV-2 的现有数据以及病毒关节炎的已知发病机制,探讨 COVID-19 后关节炎的可能免疫学机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3eaf/8456072/527661414bec/296_2021_4998_Fig1_HTML.jpg

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