Department of Spine Surgery, The Second Xiangya Hospital, Central South University, 139 Renminzhong Road, Changsha, 410011, Hunan, China.
Department of Orthopedics Surgery, General Hospital of the Central Theater Command, Wuhan, 430061, China.
World J Surg Oncol. 2021 Jun 12;19(1):171. doi: 10.1186/s12957-021-02235-0.
The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article "Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration," and to further explore some of the factors that may affect the clinical prognosis of chondroblastoma patients. We also suggest future prospective controlled studies with large samples to improve the limitations encountered by Outani et al. (World J Surg Oncol. 18(1):47, 2020) due to insufficient statistical power of variables and lack of controls.
这封给编辑的信的目的是报告最近发表的一篇文章“使用合成骨替代物治疗成软骨细胞瘤的临床结果:发生放射性关节退变的危险因素”中统计分析和变量分组存在的一些缺陷,并进一步探讨可能影响成软骨细胞瘤患者临床预后的一些因素。我们还建议未来进行大规模前瞻性对照研究,以提高由于变量统计效力不足和缺乏对照而导致 Outani 等人研究的局限性(World J Surg Oncol. 18(1):47, 2020)。