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Letter to the Editor concerning the article "Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration".致编辑的信，关于文章“使用合成骨替代物治疗成软骨细胞瘤的临床结果：发生放射性关节退变的危险因素”。
World J Surg Oncol. 2021 Jun 12;19(1):171. doi: 10.1186/s12957-021-02235-0.
2
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本文引用的文献

1
Management of cranial chondroblastoma in adults; a pooled analysis.成人颅软骨母细胞瘤的治疗；汇总分析。
Am J Otolaryngol. 2020 Jul-Aug;41(4):102486. doi: 10.1016/j.amjoto.2020.102486. Epub 2020 Apr 10.
2
Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration.采用合成骨替代物治疗成软骨细胞瘤的临床疗效：发生放射性关节退变的风险因素。
World J Surg Oncol. 2020 Mar 2;18(1):47. doi: 10.1186/s12957-020-01829-4.
3
Functional and Oncological Outcome After Treatment of Chondroblastoma With Intralesional Curettage.骨软骨母细胞瘤病灶内刮除术后的功能和肿瘤学结果
J Pediatr Orthop. 2019 Apr;39(4):e312-e317. doi: 10.1097/BPO.0000000000001293.
4
Clinical features, treatments and long-term follow-up outcomes of spinal chondroblastoma: report of 13 clinical cases in a single center.脊柱成软骨细胞瘤的临床特征、治疗方法和长期随访结果：单中心 13 例临床病例报告。
J Neurooncol. 2018 Oct;140(1):99-106. doi: 10.1007/s11060-018-2935-0. Epub 2018 Jul 2.
5
Chondroblastoma of extra-craniofacial bones: Clinicopathological analyses of 103 cases.颅外面部骨骼软骨母细胞瘤：103例临床病理分析
Pathol Int. 2017 Oct;67(10):495-502. doi: 10.1111/pin.12586.
6
Intraoperative crush smear cytology of vertebral chondroblastoma: A diagnostic challenge.椎体软骨母细胞瘤的术中压片细胞学检查：一项诊断挑战。
Diagn Cytopathol. 2018 Jan;46(1):79-82. doi: 10.1002/dc.23799. Epub 2017 Aug 23.
7
Chondroblastoma of bone in the extremities: a multicenter retrospective study.四肢骨软骨母细胞瘤：一项多中心回顾性研究。
J Bone Joint Surg Am. 2015 Jun 3;97(11):925-31. doi: 10.2106/JBJS.N.00992.
8
Treatment and prognosis of chondroblastoma.软骨母细胞瘤的治疗与预后
Clin Orthop Relat Res. 2005 Sep;438:103-9. doi: 10.1097/01.blo.0000179591.72844.c3.
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X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization.X-tile：一种用于生物标志物评估和基于结果的切点优化的新型生物信息学工具。
Clin Cancer Res. 2004 Nov 1;10(21):7252-9. doi: 10.1158/1078-0432.CCR-04-0713.

致编辑的信，关于文章“使用合成骨替代物治疗成软骨细胞瘤的临床结果：发生放射性关节退变的危险因素”。

Letter to the Editor concerning the article "Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration".

机构信息

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, 139 Renminzhong Road, Changsha, 410011, Hunan, China.

Department of Orthopedics Surgery, General Hospital of the Central Theater Command, Wuhan, 430061, China.

出版信息

World J Surg Oncol. 2021 Jun 12;19(1):171. doi: 10.1186/s12957-021-02235-0.

DOI:10.1186/s12957-021-02235-0
PMID:34118947
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8199794/
Abstract

The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article "Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration," and to further explore some of the factors that may affect the clinical prognosis of chondroblastoma patients. We also suggest future prospective controlled studies with large samples to improve the limitations encountered by Outani et al. (World J Surg Oncol. 18(1):47, 2020) due to insufficient statistical power of variables and lack of controls.

摘要

这封给编辑的信的目的是报告最近发表的一篇文章“使用合成骨替代物治疗成软骨细胞瘤的临床结果：发生放射性关节退变的危险因素”中统计分析和变量分组存在的一些缺陷，并进一步探讨可能影响成软骨细胞瘤患者临床预后的一些因素。我们还建议未来进行大规模前瞻性对照研究，以提高由于变量统计效力不足和缺乏对照而导致 Outani 等人研究的局限性（World J Surg Oncol. 18(1):47, 2020）。