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处方药监测计划对急诊科阿片类药物处方的影响。

Effect of a Prescription Drug Monitoring Program on Emergency Department Opioid Prescribing.

作者信息

Gupta Rahul, Boehmer Sue, Giampetro David, Gupta Anuj, DeFlitch Christopher J

机构信息

Penn State College of Medicine, Hershey, Pennsylvania.

Penn State Hershey Medical Center, Department of Public Health Services, Division of Biostatistics, Hershey, Pennsylvania.

出版信息

West J Emerg Med. 2021 Apr 19;22(3):756-762. doi: 10.5811/westjem.2021.1.49652.

Abstract

INTRODUCTION

Our goal was to determine whether implementation of a prescription drug monitoring program (PDMP) altered emergency department (ED) opioid prescription rates overall and in patients of different pain severities.

METHODS

We conducted this single-center, retrospective review at an academic ED. The study examined patients discharged from the ED who received opioid prescriptions, before and after the state's implementation of a PDMP (August 25, 2016). The monthly rate was a ratio of the patients given ≥ 1 opioid prescription to the ED patients with a numeric pain rating scale (NPRS) > 0. We performed an interrupted time series analysis on each demographic.

RESULTS

The overall ED opioid prescription rate decreased from 51.3% (95% confidence interval [Cl], 50.4%-52.2%) to 47.9% (95% Cl, 47.0%-48.7%). For males, this decreased from 51.1% to 46.7% (P < 0.0001), while in females it did not significantly change (51.6% to 49.7% [P = 0.0529]). For those with mild pain, the rate increased from 27.5% to 34.3% (P < 0.0001), while for those with moderate pain, it did not significantly change (42.8% to 43.5% [P = 0.5924]). For those with severe pain, the rate decreased from 66.1% to 59.6% (P < 0.0001).

CONCLUSION

We found that PDMP implementation was associated with an overall decrease in opioid prescription rates, and that patients with mild pain were prescribed opioids more often while severe pain patients were prescribed opioids less often.

摘要

引言

我们的目标是确定实施处方药监测计划(PDMP)是否会改变急诊科(ED)的总体阿片类药物处方率以及不同疼痛严重程度患者的阿片类药物处方率。

方法

我们在一家学术性急诊科进行了这项单中心回顾性研究。该研究考察了该州实施PDMP(2016年8月25日)之前和之后从急诊科出院并接受阿片类药物处方的患者。月率是指开具≥1张阿片类药物处方的患者与数字疼痛评分量表(NPRS)>0的急诊科患者的比率。我们对每个人口统计学特征进行了中断时间序列分析。

结果

急诊科总体阿片类药物处方率从51.3%(95%置信区间[Cl],50.4%-52.2%)降至47.9%(95%Cl,47.0%-48.7%)。男性的这一比例从51.1%降至46.7%(P<0.0001),而女性则无显著变化(51.6%至49.7%[P=0.0529])。轻度疼痛患者的处方率从27.5%升至34.3%(P<0.0001),而中度疼痛患者的处方率无显著变化(42.8%至43.5%[P=0.5924])。重度疼痛患者的处方率从66.1%降至59.6%(P<0.0001)。

结论

我们发现实施PDMP与阿片类药物处方率总体下降相关,轻度疼痛患者更常被开具阿片类药物,而重度疼痛患者则较少被开具阿片类药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cc0/8202985/6ac694617e95/wjem-22-756-g001.jpg

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