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对《阴性症状临床评估访谈(CAINS)》瑞典语版本进行盲法验证。

A blinded validation of the Swedish version of the Clinical Assessment Interview for Negative Symptoms (CAINS).

机构信息

Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden.

Uppsala University Hospital, Uppsala, Sweden.

出版信息

Nord J Psychiatry. 2022 Jan;76(1):44-51. doi: 10.1080/08039488.2021.1933174. Epub 2021 Jun 14.

Abstract

PURPOSE

The Clinical Assessment Interview for Negative Symptoms (CAINS) was developed in order to advance the assessment of negative symptoms. The aim of this study was to validate the Swedish version of the CAINS.

MATERIALS AND METHODS

Thirty-four out-patients with a schizophrenia spectrum disorder were recruited. All patients were videotaped while interviewed with the CAINS and the Brief Psychiatric Rating Scale (BPRS). Another rater watched the video recordings in the reverse order, enabling a blinded design. The patients also filled in self-reported measures of depression, quality of life, and social and vocational functioning. We calculated inter-rater agreement and internal consistency for the CAINS. We also calculated validity measures by correlating the subscales Motivation and Pleasure (CAINS-MAP) and Expression (CAINS-EXP) to subscales of the BPRS.

RESULTS

The blinded inter-rater agreement for the CAINS total score was high (ICC = 0.92) but slightly lower for the expression subscale (ICC = 0.76). Cronbach's alpha was 0.84 for the total score. Convergent validity with the negative symptoms subscale of BPRS was different for the blinded and the unblinded data, with a CAINS-MAP correlation of 0.10 ( = 0.580) and a CAINS-EXP correlation of 0.48 ( = 0.004) in the blinded data. The unblinded data had a CAINS-MAP correlation of 0.38 ( = 0.026) and a CAINS-EXP correlation of 0.87 ( < 0.001). Self-rated measures of anhedonia correlated to CAINS-MAP with a coefficient of 0.68 ( < 0.001), while the CAINS-EXP only had a correlation of 0.16 ( = 0.366) to these measures.

CONCLUSION

The Swedish version of the CAINS displays adequate psychometric properties in line with earlier validation studies.

摘要

目的

为了推进阴性症状的评估,开发了《阴性症状临床评估访谈》(CAINS)。本研究的目的是验证 CAINS 的瑞典语版本。

材料和方法

招募了 34 名患有精神分裂症谱系障碍的门诊患者。所有患者在接受 CAINS 和简明精神病评定量表(BPRS)访谈时都进行了录像。另一位评估员以相反的顺序观看录像,实现了盲法设计。患者还填写了抑郁、生活质量、社会和职业功能的自我报告量表。我们计算了 CAINS 的组内一致性和内部一致性。我们还通过将动机和愉悦分量表(CAINS-MAP)和表达分量表(CAINS-EXP)与 BPRS 的分量表进行相关,计算了有效性度量。

结果

CAINS 总分的盲法组内一致性很高(ICC=0.92),但表达分量表的一致性略低(ICC=0.76)。CAINS 总分的 Cronbach's alpha 为 0.84。与 BPRS 阴性症状分量表的聚合效度在盲法和非盲法数据之间有所不同,盲法数据的 CAINS-MAP 相关系数为 0.10( = 0.580),CAINS-EXP 相关系数为 0.48( = 0.004)。非盲法数据的 CAINS-MAP 相关系数为 0.38( = 0.026),CAINS-EXP 相关系数为 0.87( < 0.001)。快感缺失的自评量表与 CAINS-MAP 相关,相关系数为 0.68( < 0.001),而 CAINS-EXP 仅与这些量表相关系数为 0.16( = 0.366)。

结论

CAINS 的瑞典语版本具有与早期验证研究一致的适当心理计量学特性。

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