Consultant, Reproductive Endocrinology and Infertility, FAKIH IVF Center, Dubai, UAE.
J Med Case Rep. 2021 Jun 14;15(1):317. doi: 10.1186/s13256-021-02884-5.
Uterus didelphys results from a failure in Mullerian duct fusion and may be associated with complete or partial vaginal septa. Most cases of uterus didelphys are discovered incidentally during the workup of infertility or recurrent miscarriage. The incidence of uterus didelphys has been reported to be 0.2% in the infertile population.
A 35-year-old white Arab woman, gravida 0, parity 0, with a history of primary infertility of 8 years (a well-known male factor) presented to our infertility center. She was diagnosed as having uterus didelphys with severe male factor. The patient had three previous failed in vitro fertilization/intracytoplasmic sperm injection cycles outside our center. This is a case report of an infertile woman with uterus didelphys who conceived twice following single embryo transfer in both uterine horns successively. After the first successful pregnancy in the left uterine horn, the initial decision was to transfer the embryo to the same horn (left) because of the previous successful transfer. The very deep and long vagina forced us to reach one of the cervices, in which the embryo was placed in the right uterine horn, followed by the second successful pregnancy in the other, smaller horn. The patient gave her informed consent, both verbal and written, to use her information and images for medical publication.
Pregnancy is possible in women with uterus didelphys using single embryo transfer in in vitro fertilization/intracytoplasmic sperm injection cycles. It is recommended that both horns be given a chance.
双子宫是由于苗勒管融合失败引起的,可能伴有完全或部分阴道纵隔。大多数双子宫病例是在不孕或反复流产的检查中偶然发现的。双子宫的发病率在不孕人群中为 0.2%。
一位 35 岁的白人阿拉伯妇女,0 胎 0 产,原发性不孕 8 年(已知男方因素),到我院不孕不育中心就诊。诊断为双子宫,伴严重男方因素。该患者在我院外曾经历过 3 次失败的体外受精/胞浆内单精子注射周期。这是一例不孕的双子宫妇女的病例报告,她在双侧子宫角连续进行了单次胚胎移植后成功妊娠两次。在左侧子宫角第一次成功妊娠后,由于之前的成功移植,最初决定将胚胎转移到同侧(左侧)子宫角。非常深和长的阴道迫使我们到达一个宫颈,将胚胎放置在右侧子宫角,随后在另一侧较小的子宫角进行了第二次成功妊娠。患者已书面和口头同意使用其信息和图像进行医学出版。
在体外受精/胞浆内单精子注射周期中,通过单次胚胎移植,双子宫妇女可以怀孕。建议给两个子宫角都一个机会。