J Registry Manag. 2020 Fall;47(3):118-121.
To examine cancer incidence among the 3 Asian, non-Hispanic ethnicities with the highest frequency of cases (South Asian, Chinese, and Vietnamese).
Age-adjusted incidence rates for all invasive cancers were calculated for South Asian (Indian, Pakistani), Chinese, and Vietnamese cancer cases reported to the Massachusetts Cancer Registry (MCR). Additionally, rates were calculated for the most frequent cancers among non-Hispanic Asians (prostate, colorectal, female breast, female thyroid, lung, and male liver). The 95% confidence intervals were calculated to determine statistical significance between the rates.
South Asian and Vietnamese females had significantly elevated rates of all invasive cancers compared to Chinese females, while Chinese and South Asian females had a significantly elevated breast cancer rate. Vietnamese males had a significantly elevated rate of all invasive cancers, liver cancer, and lung cancer compared to the other 2 groups. Due to the high rates of lung cancer among Vietnamese males, MCR current/previous smoking data were compared for all cancers. Among Vietnamese, Chinese, and South Asian male cancer cases, current/ previous smoking percentages were 64%, 51%, and 35%, respectively.
Our analyses showed a significant difference of rates for several cancers by specific Asian ethnicity within the broader Asian, non-Hispanic race category. Differences in tobacco use, maternal hepatitis B infection, and diet likely contribute to some of the differences. These data can aid in the development of prevention programs, such as smoking cessation and mammography screening that are culturally and linguistically specific within this large and diverse group.
研究发病率最高的 3 种亚洲非西班牙裔族群（南亚裔、华裔和越南裔）中的癌症发病率。
根据向马萨诸塞州癌症登记处（MCR）报告的南亚裔（印度裔、巴基斯坦裔）、华裔和越南裔癌症病例，计算所有浸润性癌症的年龄调整发病率。此外，还计算了非西班牙裔亚裔最常见癌症（前列腺癌、结直肠癌、女性乳腺癌、女性甲状腺癌、肺癌和男性肝癌）的发病率。计算了 95%置信区间以确定各率之间的统计学意义。
与华裔女性相比，南亚裔和越南裔女性所有浸润性癌症的发病率明显升高，而华裔和南亚裔女性的乳腺癌发病率明显升高。与其他两组相比，越南裔男性的所有浸润性癌症、肝癌和肺癌发病率明显升高。由于越南裔男性的肺癌发病率较高，因此对所有癌症的 MCR 当前/既往吸烟数据进行了比较。在越南裔、华裔和南亚裔男性癌症患者中，当前/既往吸烟的百分比分别为 64%、51%和 35%。
我们的分析表明，在更广泛的亚洲非西班牙裔人群中，按特定亚洲族群划分，几种癌症的发病率存在显著差异。烟草使用、母婴乙型肝炎感染和饮食的差异可能导致了部分差异。这些数据可以帮助制定针对这个庞大而多样化群体的文化和语言特定的预防计划，例如戒烟和乳房 X 光筛查。
