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Human immunodeficiency virus-associated heart failure in sub-Saharan Africa: evolution in the epidemiology, pathophysiology, and clinical manifestations in the antiretroviral era.撒哈拉以南非洲地区与人类免疫缺陷病毒相关的心力衰竭:抗逆转录病毒时代的流行病学、病理生理学及临床表现的演变
ESC Heart Fail. 2016 Sep;3(3):158-167. doi: 10.1002/ehf2.12087. Epub 2016 Mar 3.
2
Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015.1990年至2015年全球、区域和国家10种心血管疾病病因负担
J Am Coll Cardiol. 2017 Jul 4;70(1):1-25. doi: 10.1016/j.jacc.2017.04.052. Epub 2017 May 17.
3
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.1980 - 2015年全球、区域和国家249种死因的预期寿命、全死因死亡率和死因别死亡率:全球疾病负担研究2015的系统分析
Lancet. 2016 Oct 8;388(10053):1459-1544. doi: 10.1016/S0140-6736(16)31012-1.
4
Global Disparities of Hypertension Prevalence and Control: A Systematic Analysis of Population-Based Studies From 90 Countries.高血压患病率与控制情况的全球差异:来自90个国家基于人群研究的系统分析
Circulation. 2016 Aug 9;134(6):441-50. doi: 10.1161/CIRCULATIONAHA.115.018912.
5
Endemic Cardiovascular Diseases of the Poorest Billion.最贫困的十亿人所特有的心血管疾病。
Circulation. 2016 Jun 14;133(24):2561-75. doi: 10.1161/CIRCULATIONAHA.116.008731.
6
Prevalence and associated risk factors of hypertension amongst adults in a rural community of Limpopo Province, South Africa.南非林波波省一个农村社区成年人高血压的患病率及相关危险因素
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Non-communicable diseases in South Africa: a challenge to economic development.南非的非传染性疾病:对经济发展的一项挑战。
S Afr Med J. 2014 Jul 31;104(10):647. doi: 10.7196/samj.8727.
8
Health and health care in South Africa--20 years after Mandela.曼德拉之后二十年的南非健康与医疗保健
N Engl J Med. 2014 Oct 2;371(14):1344-53. doi: 10.1056/NEJMsr1405012. Epub 2014 Sep 29.
9
Medical inpatient mortality at Groote Schuur Hospital, Cape Town, South Africa, 2002-2009.2002-2009 年南非开普敦格罗特舒尔医院住院患者病死率。
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Contribution of the human immunodeficiency virus/acquired immunodeficiency syndrome epidemic to de novo presentations of heart disease in the Heart of Soweto Study cohort.人类免疫缺陷病毒/获得性免疫缺陷综合征流行对索韦托心脏研究队列中新发心脏病的影响。
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南非一家地区医院心血管疾病的谱、患病率和院内结局:一项回顾性研究。

The spectrum, prevalence and in-hospital outcomes of cardiovascular diseases in a South African district hospital: a retrospective study.

机构信息

Cardiac Clinic, Groote Schuur Hospital, Cape Town, South Africa. Email:

Department of Medicine, Dora Nginza Provincial Hospital, Port Elizabeth, South Africa.

出版信息

Cardiovasc J Afr. 2021;32(5):237-242. doi: 10.5830/CVJA-2021-016. Epub 2021 Jun 10.

DOI:10.5830/CVJA-2021-016
PMID:34128952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8756043/
Abstract

INTRODUCTION

The increasing prevalence of cardiovascular risk factors in South African rural communities is well reported. However, the prevalence of cardiovascular disease (CVD) leading to hospital admission and related in-hospital mortality in rural and semi-rural hospitals is unknown.

METHODS

We conducted a retrospective review of hospital records for patients admitted to the Department of Internal Medicine at Dora Nginza Hospital in Port Elisabeth, South Africa between 1 April and 31 October 2016. The study focused on patients who received a primary diagnosis of CVD.

RESULTS

During the seven-month study period, 4 884 patients were admitted to the unit, 1 325 of whom received a primary diagnosis of CVD, giving a prevalence of 27%. Patients with CVD had a mean (standard deviation) age of 60 (± 15) years, 32% of this patient population was younger than 55 years and 65% were female. Furthermore, 94% had a background medical history of systemic hypertension and 30% of diabetes mellitus. The three leading cardiovascular causes of hospital admission were stroke (38%), hypertensive heart disease plus heart failure (33%), and hypertensive emergency/urgency (18%). In-hospital outcome: 12.4% of patients admitted for CVD died during the index hospitalisation and strokes were responsible for 70% of the deaths.

CONCLUSIONS

The prevalence of CVD in this cohort was high and accounted for significant morbidity and mortality. Systemic hypertension was a leading risk factor in our cohort and we need to intensify efforts to diagnose and treat systemic hypertension.

摘要

简介

南非农村社区心血管危险因素的患病率不断上升,这一情况已得到充分报道。然而,农村和半农村医院因心血管疾病(CVD)导致住院及相关院内死亡率的流行情况尚不清楚。

方法

我们对 2016 年 4 月 1 日至 10 月 31 日期间在南非伊丽莎白港多娜宁加医院内科住院的患者的医院记录进行了回顾性分析。本研究的重点是接受 CVD 主要诊断的患者。

结果

在七个月的研究期间,共有 4884 名患者被收入该科室,其中 1325 名患者被诊断为 CVD,患病率为 27%。CVD 患者的平均(标准差)年龄为 60(±15)岁,其中 32%的患者年龄小于 55 岁,65%为女性。此外,94%的患者有系统性高血压病史,30%的患者有糖尿病病史。导致住院的三大心血管疾病分别为中风(38%)、高血压性心脏病伴心力衰竭(33%)和高血压急症/紧急情况(18%)。住院期间的结局:12.4%因 CVD 入院的患者在住院期间死亡,其中中风导致了 70%的死亡。

结论

该队列中 CVD 的患病率较高,导致了较高的发病率和死亡率。系统性高血压是本队列中的主要危险因素,我们需要加强努力来诊断和治疗系统性高血压。