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当代心力衰竭患者中植入式心律转复除颤器的应用

Contemporary ICD Use in Patients with Heart Failure.

作者信息

Spartalis Michael, Nakajima Kenzaburo, Zweiker David, Spartalis Eleftherios, Iliopoulos Dimitrios C, Siasos Gerasimos

机构信息

Arrhythmia Unit, IRCCS San Raffaele Scientific Institute, San Raffaele University Hospital, Milan, Italy.

Laboratory of Experimental Surgery and Surgical Research 'N. S. Christeas', Medical School, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

Cardiol Ther. 2021 Dec;10(2):313-324. doi: 10.1007/s40119-021-00225-7. Epub 2021 Jun 15.

DOI:10.1007/s40119-021-00225-7
PMID:34129228
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8555039/
Abstract

Despite constant breakthroughs in heart failure (HF) therapy, the population of HF patients resume to grow and is linked to increased mortality and morbidity. Ventricular arrhythmias (VA) are one of the leading causes of mortality in HF subjects. Implantable cardioverter-defibrillators (ICDs) are currently the gold standard in treatment, preventing arrhythmic sudden cardiac death (SCD) episodes. However, the death rates related to HF remain elevated, as not all HF subjects benefit equally. Cardiac resynchronization therapy (CRT) has emerged as a novel approach for HF patients. These devices have been thoroughly investigated in major randomized controlled studies but continue to be underutilized in various countries. This review discusses the use of ICD in HF populations on top of treatments.

摘要

尽管心力衰竭(HF)治疗不断取得突破,但HF患者的数量仍在持续增长,且与死亡率和发病率的增加相关。室性心律失常(VA)是HF患者死亡的主要原因之一。植入式心脏复律除颤器(ICD)是目前治疗的金标准,可预防心律失常性心源性猝死(SCD)发作。然而,与HF相关的死亡率仍然居高不下,因为并非所有HF患者都能平等受益。心脏再同步治疗(CRT)已成为治疗HF患者的一种新方法。这些设备已在主要的随机对照研究中得到充分研究,但在各个国家仍未得到充分利用。本综述讨论了在HF人群中除其他治疗外使用ICD的情况。

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1
Contemporary ICD Use in Patients with Heart Failure.当代心力衰竭患者中植入式心律转复除颤器的应用
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J Cardiovasc Dev Dis. 2022 Apr 16;9(4):120. doi: 10.3390/jcdd9040120.
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Comparable Efficacy in Ischemic and Non-Ischemic ICD Recipients for the Primary Prevention of Sudden Cardiac Death.缺血性和非缺血性植入式心律转复除颤器(ICD)受者在心脏性猝死一级预防中的疗效相当。
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本文引用的文献

1
Subcutaneous or Transvenous Defibrillator Therapy.皮下或经静脉除颤器治疗。
N Engl J Med. 2020 Aug 6;383(6):526-536. doi: 10.1056/NEJMoa1915932.
2
The genesis of ventricular arrhythmias in heart failure patients is based on alterations in cardiac mechanical, morphological, metabolic, electrophysiological properties, and neurohumoral remodeling.心力衰竭患者室性心律失常的发生基于心脏机械、形态、代谢、电生理特性以及神经体液重塑的改变。
J Cardiol. 2020 Sep;76(3):322-323. doi: 10.1016/j.jjcc.2020.03.005. Epub 2020 Apr 22.
3
Is the clinical benefit of implantable cardioverter-defibrillators in heart failure patients declining?植入式心脏复律除颤器对心力衰竭患者的临床益处是否在下降?
J Cardiol. 2020 May;75(5):583-584. doi: 10.1016/j.jjcc.2020.02.002. Epub 2020 Feb 27.
4
Devices in Heart Failure Patients-Who Benefits From ICD and CRT?心力衰竭患者的设备——谁能从植入式心脏复律除颤器(ICD)和心脏再同步治疗(CRT)中获益?
Front Cardiovasc Med. 2019 Aug 13;6:111. doi: 10.3389/fcvm.2019.00111. eCollection 2019.
5
Electrical Storm: Current Evidence, Clinical Implications, and Future Perspectives.电风暴:当前证据、临床意义和未来展望。
Curr Cardiol Rep. 2019 Jul 27;21(9):96. doi: 10.1007/s11886-019-1190-0.
6
Cardiac Implantable Electronic Device Therapy in Heart Failure.心力衰竭的心脏植入式电子设备治疗。
Circ Res. 2019 May 24;124(11):1584-1597. doi: 10.1161/CIRCRESAHA.118.313571.
7
On-treatment comparison between corrective His bundle pacing and biventricular pacing for cardiac resynchronization: A secondary analysis of the His-SYNC Pilot Trial.校正希氏束起搏与双心室起搏治疗心脏再同步化的治疗中比较:His-SYNC 试验的二次分析。
Heart Rhythm. 2019 Dec;16(12):1797-1807. doi: 10.1016/j.hrthm.2019.05.009. Epub 2019 May 13.
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His Bundle Pacing: A New Strategy for Physiological Ventricular Activation.希氏束起搏:生理性心室激动的新策略。
J Am Heart Assoc. 2019 Mar 19;8(6):e010972. doi: 10.1161/JAHA.118.010972.
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Clinical Outcomes of His Bundle Pacing Compared to Right Ventricular Pacing.希氏束起搏与右心室起搏的临床转归比较。
J Am Coll Cardiol. 2018 May 22;71(20):2319-2330. doi: 10.1016/j.jacc.2018.02.048. Epub 2018 Mar 10.
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CRT Survey II: a European Society of Cardiology survey of cardiac resynchronisation therapy in 11 088 patients-who is doing what to whom and how?CRT 调查 II:欧洲心脏病学会对 11088 例心脏再同步治疗患者的调查——谁对谁做了什么以及怎么做的?
Eur J Heart Fail. 2018 Jun;20(6):1039-1051. doi: 10.1002/ejhf.1142. Epub 2018 Feb 19.