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经尿道前列腺水(电)切术联合选择性双极电切术与钬激光前列腺剜除术(HoLEP)治疗前列腺增生的围手术期出血比较。

Aquablation with subsequent selective bipolar cauterization versus holmium laser enucleation of the prostate (HoLEP) with regard to perioperative bleeding.

机构信息

Center for Minimally Invasive and Robotic Urology, Augusta Bochum, Witten/Herdecke University, Germany.

出版信息

Can J Urol. 2021 Jun;28(3):10685-10690.

PMID:34129462
Abstract

INTRODUCTION

To compare the surgical methods of Aquablation followed by selective hemostasis by bipolar cauterization with holmium laser enucleation of the prostate (HoLEP) with regard to the risk of perioperative bleeding complications.

MATERIALS AND METHODS

A retrospective comparison was carried out on a total of 382 patients who had undergone either Aquablation (n = 167) or HoLEP (n = 215) at our hospital between April 2018 and July 2020. The following were studied: Hb loss, the need for packed red blood cell transfusions and surgical revisions due to bleeding from the prostatic fossa.

RESULTS

Transfusions were not necessary in the Aquablation group, while one man who underwent HoLEP had to receive a transfusion. Revision surgery due to bleeding was necessary during the early postoperative course in 13.2% of Aquablations and in 9.8% of HoLEPs (statistically not significant; p = 0.329). The perioperative Hb loss was comparable in both entire collectives (Aquablation 1.37 +/- 1.13 mg/dL, HoLEP 1.22 +/- 1.03 mg/dL; statistically not significant; p = 0.353). For subgroup analysis the groups Aquablation and HoLEP were into three subgroups respectively according to sonographically determined preoperative prostate volume ('small' < 40 mL, 'medium' 41-80 mL, 'large' > 80 mL). There were no significant differences between the subgroups regarding need for transfusions and hematuria-related complications.

CONCLUSIONS

The rate of perioperative hematuria related complications of Aquablation with subsequent selective hemostasis equals those found after holmium laser enucleation.

摘要

介绍

比较经 Aquablation 治疗后选择性双极电凝止血与经钬激光前列腺剜除术(HoLEP)治疗前列腺的围手术期出血并发症风险。

材料和方法

回顾性比较了 2018 年 4 月至 2020 年 7 月期间在我院接受 Aquablation(n = 167)或 HoLEP(n = 215)治疗的 382 例患者。研究内容包括:血红蛋白丢失、因前列腺窝出血需要输血和手术修正。

结果

Aquablation 组无需输血,而接受 HoLEP 治疗的 1 名男性需要输血。Aquablation 组有 13.2%的患者在早期术后需要因出血进行修正手术,HoLEP 组有 9.8%的患者需要进行修正手术(无统计学意义;p = 0.329)。两组整个患者群体的围手术期血红蛋白丢失相当(Aquablation 组为 1.37 +/- 1.13mg/dL,HoLEP 组为 1.22 +/- 1.03mg/dL;无统计学意义;p = 0.353)。对于亚组分析,根据术前超声确定的前列腺体积(“小”<40mL、“中”41-80mL、“大”>80mL),将 Aquablation 和 HoLEP 两组分别分为三个亚组。在输血需求和血尿相关并发症方面,亚组之间没有显著差异。

结论

经 Aquablation 治疗后选择性止血的围手术期血尿相关并发症发生率与钬激光前列腺剜除术相当。

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