Radiology and Nuclear Medicine, University Medical Center Utrecht and Utrecht University, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Image Sciences Institute, University Medical Center Utrecht and Utrecht University, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Eur Radiol. 2022 Jan;32(1):517-523. doi: 10.1007/s00330-021-08023-4. Epub 2021 Jun 16.
This study evaluates the performance of a mobile and compact hybrid C-arm scanner (referred to as IXSI) that is capable of simultaneous acquisition of 2D fluoroscopic and nuclear projections and 3D image reconstruction in the intervention room.
The impact of slightly misaligning the IXSI modalities (in an off-focus geometry) was investigated for the reduction of the fluoroscopic and nuclear interference. The 2D and 3D nuclear image quality of IXSI was compared with a clinical SPECT/CT scanner by determining the spatial resolution and sensitivity of point sources and by performing a quantitative analysis of the reconstructed NEMA image quality phantom. The 2D and 3D fluoroscopic image of IXSI was compared with a clinical CBCT scanner by visualizing the Fluorad A+D image quality phantom and by visualizing a reconstructed liver nodule phantom. Finally, the feasibility of dynamic simultaneous nuclear and fluoroscopic imaging was demonstrated by injecting an anthropomorphic phantom with a mixture of iodinated contrast and Tc.
Due to the divergent innovative hybrid design of IXSI, concessions were made to the nuclear and fluoroscopic image qualities. Nevertheless, IXSI realizes unique image guidance that may be beneficial for several types of procedures.
• IXSI can perform time-resolved planar (2D) simultaneous fluoroscopic and nuclear imaging. • IXSI can perform SPECT/CBCT imaging (3D) inside the intervention room.
本研究评估了一种可在介入室内同时采集二维透视和核投影并进行三维图像重建的移动紧凑型混合 C 臂扫描仪（简称 IXSI）的性能。
研究了略微错开 IXSI 模式（失焦几何形状）对减少透视和核干扰的影响。通过确定点源的空间分辨率和灵敏度，并对重建的 NEMA 图像质量体模进行定量分析，比较了 IXSI 的二维和三维核图像质量与临床 SPECT/CT 扫描仪的性能。通过可视化 Fluorad A+D 图像质量体模和可视化重建的肝结节体模，比较了 IXSI 的二维和三维透视图像与临床 CBCT 扫描仪的性能。最后，通过向拟人化体模中注入碘造影剂和 Tc 的混合物，证明了动态同时进行核和透视成像的可行性。
由于 IXSI 具有独特的混合设计，因此在核和透视图像质量方面做出了一些让步。然而，IXSI 实现了独特的图像引导，这可能对多种类型的手术有益。
IXSI 可进行时间分辨的平面（二维）透视和核同时成像。
IXSI 可在介入室内进行 SPECT/CBCT 成像（三维）。
