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Fusion genes in acute myeloid leukemia: do acute myeloid leukemia diagnostics need to fuse with RNA-sequencing?

作者信息

Thol Felicitas

机构信息

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

出版信息

Haematologica. 2022 Jan 1;107(1):44-45. doi: 10.3324/haematol.2021.278983.

DOI:10.3324/haematol.2021.278983
PMID:34134473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8719096/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6d/8719096/1ae6cbe10ed1/10744.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6d/8719096/1ae6cbe10ed1/10744.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f6d/8719096/1ae6cbe10ed1/10744.fig1.jpg

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本文引用的文献

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Haematologica. 2022 Jan 1;107(1):100-111. doi: 10.3324/haematol.2021.278436.
2
NRG1 fusion-driven tumors: biology, detection, and the therapeutic role of afatinib and other ErbB-targeting agents.NRG1 融合驱动的肿瘤：生物学、检测以及阿法替尼和其他 ErbB 靶向药物的治疗作用。
Ann Oncol. 2020 Dec;31(12):1693-1703. doi: 10.1016/j.annonc.2020.08.2335. Epub 2020 Sep 9.
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Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms.
在血液肿瘤中发现并鉴定可靶向的 NTRK 点突变。
Blood. 2020 Jun 11;135(24):2159-2170. doi: 10.1182/blood.2019003691.
4
Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods.基于读长比对和从头拼接融合转录本的融合转录本检测准确性评估。
Genome Biol. 2019 Oct 21;20(1):213. doi: 10.1186/s13059-019-1842-9.
5
Measurable residual disease monitoring by NGS before allogeneic hematopoietic cell transplantation in AML.在 AML 患者进行异基因造血细胞移植前，通过 NGS 进行可测量残留病监测。
Blood. 2018 Oct 18;132(16):1703-1713. doi: 10.1182/blood-2018-02-829911. Epub 2018 Sep 6.
6
Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.拉罗替尼在成人和儿童TRK融合阳性癌症中的疗效。
N Engl J Med. 2018 Feb 22;378(8):731-739. doi: 10.1056/NEJMoa1714448.
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Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.成人急性髓系白血病的诊断与管理：2017年国际专家小组的欧洲白血病网络（ELN）建议
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