Uldry P A, Regli F
Service de neurologie, Centre hospitalier universitaire vaudois, Lausanne.
Schweiz Med Wochenschr. 1988 Jul 12;118(27-28):1029-31.
Unilateral facial palsies were observed in three patients with positive serology for HIV. Two patients presented a second unilateral peripheral seventh nerve palsy after extraction of a tooth. Recovery was complete in each case. Peripheral neuropathies are present in 20% of cases with AIDS but cranial neuropathies are uncommon, affecting only 2 to 3% of patients. The seventh and the fifth are the most frequent cranial nerves involved. The reported isolation of HIV in the cerebrospinal fluid and from the nerve suggests a direct role of this agent. In this study an indirect mechanism such as a vascular spasm may also favour the occurrence of these facial palsies.
在3例HIV血清学检测呈阳性的患者中观察到单侧面瘫。2例患者在拔牙后出现了第二次单侧周围性面神经麻痹。每例患者均完全康复。20%的艾滋病患者存在周围神经病变,但颅神经病变并不常见,仅影响2%至3%的患者。第七和第五颅神经是最常受累的颅神经。据报道,在脑脊液和神经中分离出HIV,提示该病原体起直接作用。在本研究中,血管痉挛等间接机制也可能促使这些面瘫的发生。