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[人类免疫缺陷病毒感染患者的周围性面瘫相关性研究]

[Association of peripheral facial paralysis in patients with human immunodeficiency virus infection].

作者信息

Casanova-Sotolongo P, Casanova-Carrillo P

机构信息

Servicio de Neurología; Hospital Central de Beira Mozambique, Beira, Mozambique.

出版信息

Rev Neurol. 2001;32(4):327-30.

Abstract

INTRODUCTION

Neurological disorders are common in patients infected with the human immunodeficiency virus (HIV). The objective of this study is to show the possible association of peripheral facial paralysis (PFP) in persons who test positive for HIV, which because of the characteristics of outpatient management is important in basic medical attention.

PATIENTS AND METHODS

The scope of our study included all patients observed in 1998 and the first six months of 1999 who had PFP, and in whom detailed clinical history, physical examination by a neurologist, laboratory tests and HIV serological tests were done.

RESULTS

We found that 89.1% of the patients with PFP were seropositive. The facial paralysis showed similar characteristics to Bell s palsy, with complete recovery after four weeks in 66.6% of this group of patients. The seronegative patients also recovered completely but took longer to do so. In two cases the PFP was associated with obvious features of AIDS.

CONCLUSIONS

In the literature reviewed we have not found such a large group of patients with PFP associated with HIV+. However, it is obvious that there is an increase in facial paralysis which is in proportion to the increase in HIV+ persons. The results of our study suggest to us that HIV should be tested for in patients with PFP.

摘要

引言

神经疾病在感染人类免疫缺陷病毒(HIV)的患者中很常见。本研究的目的是揭示HIV检测呈阳性者出现周围性面瘫(PFP)的可能关联,鉴于门诊管理的特点,这在基础医疗护理中很重要。

患者与方法

我们的研究范围包括1998年及1999年头六个月观察到的所有患有PFP的患者,对他们进行了详细的临床病史询问、由神经科医生进行的体格检查、实验室检查以及HIV血清学检测。

结果

我们发现89.1%的PFP患者血清呈阳性。面瘫表现出与贝尔面瘫相似的特征,该组患者中有66.6%在四周后完全恢复。血清阴性的患者也完全恢复了,但所需时间更长。有两例PFP与明显艾滋病特征相关。

结论

在我们查阅的文献中,尚未发现如此大量的与HIV阳性相关的PFP患者群体。然而,面瘫明显增多,且与HIV阳性者数量的增加成比例,这一点是显而易见的。我们的研究结果提示,对于PFP患者应进行HIV检测。

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