Huang Qiulan, Huang Yanting, Liu Jianping
Department of Endocrinology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Int J Endocrinol. 2021 May 28;2021:9938658. doi: 10.1155/2021/9938658. eCollection 2021.
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti-inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin-producing cells (IPCs), providing an inexhaustible supply of functional cells for cell replacement therapy and disease modeling for diabetes. MSC therapy may be the most promising strategy for diabetes mellitus because of these significant merits. In this paper, we focused on MSC therapy for diabetes.
间充质干细胞(MSCs)是成体干细胞(ASCs),以修复受损细胞、发挥抗炎反应和产生免疫调节作用而闻名,这些细胞可被显著诱导分化为胰岛素生成细胞(IPCs),为细胞替代疗法和糖尿病疾病建模提供源源不断的功能细胞。由于这些显著优点,间充质干细胞疗法可能是治疗糖尿病最有前景的策略。在本文中,我们重点关注间充质干细胞治疗糖尿病的方法。