Schincaglia Raquel M, Pimentel Gustavo D, Peixoto Maria do Rosário G, Cuppari Lilian, Mota João Felipe
Clinical and Sports Nutrition Research Laboratory (Labince), Faculty of Nutrition, Federal University of Goiás (UFG), Goiânia 740303-060, Brazil.
Faculty of Nutrition, Federal University of Goiás (UFG), Goiânia 740303-060, Brazil.
Evid Based Complement Alternat Med. 2021 May 26;2021:3187305. doi: 10.1155/2021/3187305. eCollection 2021.
Gastrointestinal symptoms are common in patients in hemodialysis treatment and were frequently associated with low intake of dietary fibers and liquids, oral iron supplementation, phosphate binders, and low level of physical activity. Thus, the aim of this study was to evaluate the effect of baru almond oil in comparison with mineral oil supplementation on bowel habits of hemodialysis patients. Thirty-five patients on hemodialysis (57% men, 49.9 ± 12.4 years) were enrolled in a 12-week single-blind clinical trial. Patients were allocated (1 : 2) by sex and age into (1) the mineral group: 10 capsules per day of mineral oil (500 mg each) or (2) the baru almond oil group: 10 capsules per day of baru almond oil (500 mg each). Bowel habits were assessed by the Rome IV criteria, Bristol scale, and self-perception of constipation. Food consumption, physical activity level, and time spent sitting were also evaluated at the baseline and at the end of the study. After 12 weeks of supplementation, the baru almond oil group showed reduced Rome IV score (6.1 ± 5.5 vs 2.8 ± 4.3, =0.04) and the straining on the evacuation score (1.2 ± 1.4 vs 0.4 ± 0.7; =0.04), while the mineral group did not show any change in the parameters. The frequency of self-perception of constipation was lower in the baru almond oil group after intervention (45.0% vs 15.0%, =0.04). Baru almond oil improved bowel habit and the straining on evacuation in hemodialysis patients.
胃肠道症状在接受血液透析治疗的患者中很常见,且常与膳食纤维和液体摄入不足、口服铁补充剂、磷结合剂以及身体活动水平低有关。因此,本研究的目的是评估与补充矿物油相比,baru杏仁油对血液透析患者排便习惯的影响。35名接受血液透析的患者(57%为男性,年龄49.9±12.4岁)参加了一项为期12周的单盲临床试验。患者按性别和年龄(1∶2)分为(1)矿物油组:每天服用10粒矿物油胶囊(每粒500毫克);或(2)baru杏仁油组:每天服用10粒baru杏仁油胶囊(每粒500毫克)。通过罗马IV标准、布里斯托量表和便秘自我认知来评估排便习惯。在基线和研究结束时还评估了食物摄入量、身体活动水平和久坐时间。补充12周后,baru杏仁油组的罗马IV评分降低(6.1±5.5对2.8±4.3,P=0.04),排便时用力评分降低(1.2±1.4对0.4±0.7;P=0.04),而矿物油组的这些参数没有变化。干预后,baru杏仁油组便秘自我认知的频率较低(45.0%对15.0%,P=0.04)。baru杏仁油改善了血液透析患者的排便习惯和排便时的用力情况。